FIGURE

Fig. 6

ID

ZDB-FIG-110318-39

Publication

Curtin et al., 2011 - Zebrafish wnt9a is expressed in pharyngeal ectoderm and is required for palate and lower jaw development

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Fig. 6

Knockdown of wnt9a does not alter early cranial neural crest migration. Embryos injected with wnt9a mismatch control (MM) (a–c), and translation-blocking morpholino (MO) (e–h). Timepoints are 24 hpf (a, b, d and e), and 42 hpf (c and f). Embryos are mounted in lateral view with head toward left detected with dlx2a riboprobe (a and d), detected with sox10 riboprobe in dorsal view with head toward top (b and e), and gsc riboprobe in ventral view (c and f). These neural crest markers all demonstrate normal early migration to appropriate pharyngeal arch positions, in mismatch (MM) and translation-blocking (MO) morpholino injected embryos. No developmental delay was observed.

Expression Data

Genes:	dlx2a gsc sox10
Fish:	TU TU + MO1-wnt9a
Knockdown Reagent:	MO1-wnt9a
Anatomical Terms:	cranial neural crest cell otic vesicle pharyngeal arch 1 cranial neural crest cell pharyngeal arch 2 cranial neural crest cell
Stage Range:	Prim-5 to High-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Mechanisms of Development, 128(1-2), Curtin, E., Hickey, G., Kamel, G., Davidson, A.J., and Liao, E.C., Zebrafish wnt9a is expressed in pharyngeal ectoderm and is required for palate and lower jaw development, 104-115, Copyright (2011) with permission from Elsevier. Full text @ Mech. Dev.