FIGURE

Fig. 6

ID
ZDB-FIG-100913-27
Publication
Clifton et al., 2010 - Identification of novel inhibitors of dietary lipid absorption using zebrafish
Other Figures
All Figure Page
Back to All Figure Page
Fig. 6

Ezetimibe inhibits lipid metabolism in zebrafish larvae.

(A) Bright field image of a 6 day post-fertilization wild type (wt) zebrafish larva, lateral view. Red asterisk - intestine. (B–I) Gallbladder (red arrow) and intestinal (red asterisk) fluorescence in live 6 day post-fertilization wt and ezetimibe (50 μM) treated larvae following ingestion of fluorescent lipid reporters. (B, C) NBD-cholesterol; (D, G) PED6, (E, H) C16 bodipy (BdpC16), and (F, I) C5 bodipy (BdpC5). (J) Mean reduction in lipid reporter metabolism in ezetimibe vs wild type larvae. Error bars – standard deviation.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One