FIGURE

Fig. 4

ID

ZDB-FIG-100913-25

Publication

Clifton et al., 2010 - Identification of novel inhibitors of dietary lipid absorption using zebrafish

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Fig. 4

Digestive protease activity in compound treated larvae.

(A–C) Representative fluorescent images of live wild type and compound treated larvae following ingestion of a quenched bodipy conjugate of casein. Bright fluorescence is seen in the intestine of the wild type larva and the larva treated with compound 2, while minimal fluorescence is detected in the intestine of the larva treated with compound 7. (D) Quantification of the effect of the active compounds on bodipy-casein metabolism, as determined by gall bladder and intestinal fluorescence measured from individual larvae. Arrow - gallbladder; asterisk - intestine. Error bars – standard deviation. All compounds used at 25 μM.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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