|ZFIN ID: ZDB-FIG-100903-47|
Fig. 7 Knockdown of Moesin1 results in extensive loss of adherens junctions without affecting ZO-1-associated junctions. (A-F) Confocal images of ISVs in the Tg(fli1:egfp)y1 zebrafish embryos that were probed for ZO-1 (red) at 54 hpf. (A-C) ZO-1-associated junctions are seen in a control embryo. (D-F) The ZO-1-associated junctions (arrow) are observed in Moesin1 knockdown embryos but are not well separated from one another. (G-L) Confocal images of ISVs in Tg(fli1:egfp)y1 embryos labeled with Ve-cadherin (red) at 54 hpf. (G-I) Ve-cadherin labeling in a control embryo. (J-L) Moesin1 knockdown causes an extensive loss of Ve-cadherin labeling (arrowheads); some weak Ve-cadherin signals are observed (arrows).
|Ab1-cdh5||y1Tg + MO1-msna||standard conditions||Long-pec||IHC|
|y1Tg + MO1-msna||standard conditions||Long-pec||IFL|
|IHC||y1Tg + MO1-msna||standard conditions||Long-pec|
|y1Tg + MO1-msna||standard conditions||Long-pec||adherens junction organization process quality, abnormal|
|Long-pec||blood vessel endothelial cell adherens junction physical object quality, abnormal|
|Acknowledgments:||ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development|