ZFIN ID: ZDB-FIG-100625-3
Ebermann et al., 2010 - PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome. J. Clin. Invest.   120(6):1812-1823 Full text @ J. Clin. Invest.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes: adgrv1, pdzd7a
Antibodies: Ab1-adgrv1, Ab1-pdzd7a, Ab1-tuba
Fish: AB, AB + MO1-pdzd7a
Knockdown Reagent: MO1-pdzd7a
Anatomical Terms: eye photoreceptor cell photoreceptor connecting cilium, eye photoreceptor cell synapse, retina neuron projection
Stage: Day 5
PHENOTYPE:
Fish: AB + MO1-pdzd7a, AB + MO1-ush2a, AB + MO1-adgrv1 + MO1-pdzd7a, AB + MO1-pdzd7a + MO1-ush2a
Knockdown Reagents: MO1-adgrv1, MO1-pdzd7a, MO1-ush2a
Observed In: anterior crista stereocilium bundle, eye photoreceptor cell, eye photoreceptor cell photoreceptor connecting cilium, eye photoreceptor cell development, inner ear receptor cell development
Stage: Day 5

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
adgrv1 Ab1-adgrv1 AB control Day 5 eye photoreceptor cell photoreceptor connecting cilium IHC
Ab1-adgrv1 Day 5 eye photoreceptor cell synapse IHC
Ab1-adgrv1 AB + MO1-pdzd7a standard conditions Day 5 Not Detected eye photoreceptor cell photoreceptor connecting cilium IHC
Ab1-adgrv1 Day 5 eye photoreceptor cell synapse IHC
pdzd7a Ab1-pdzd7a AB control Day 5 eye photoreceptor cell photoreceptor connecting cilium IHC
Ab1-pdzd7a Day 5 Not Detected eye photoreceptor cell synapse IHC
Ab1-pdzd7a AB + MO1-pdzd7a standard conditions Day 5 Not Detected eye photoreceptor cell photoreceptor connecting cilium IHC
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-tuba IHC AB control Day 5 eye photoreceptor cell photoreceptor connecting cilium
IHC Day 5 retina neuron projection
IHC AB + MO1-pdzd7a standard conditions Day 5 eye photoreceptor cell photoreceptor connecting cilium
IHC Day 5 retina neuron projection
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO1-adgrv1 + MO1-pdzd7a standard conditions Day 5 eye photoreceptor cell apoptotic, abnormal
AB + MO1-pdzd7a standard conditions Day 5 anterior crista stereocilium bundle malformed, abnormal
Day 5 eye photoreceptor cell apoptotic, abnormal
Day 5 eye photoreceptor cell development process quality, abnormal
Day 5 eye photoreceptor cell photoreceptor connecting cilium physical object quality, abnormal
Day 5 inner ear receptor cell development process quality, abnormal
AB + MO1-pdzd7a + MO1-ush2a standard conditions Day 5 eye photoreceptor cell apoptotic, abnormal
AB + MO1-ush2a standard conditions Day 5 eye photoreceptor cell apoptotic, abnormal
Full text @ J. Clin. Invest.