Gene

adgrv1

ID
ZDB-GENE-040624-6
Name
adhesion G protein-coupled receptor V1
Symbol
adgrv1 Nomenclature History
Previous Names
  • vlgr1 (1)
  • gpr98
  • mass1 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have G protein-coupled receptor activity; G-protein alpha-subunit binding activity; and adenylate cyclase inhibitor activity. Involved in eye photoreceptor cell development. Predicted to localize to integral component of membrane; photoreceptor inner segment; and stereocilium membrane. Human ortholog(s) of this gene implicated in Usher syndrome type 2C and familial febrile seizures 4. Is expressed in integument; nervous system; and pleuroperitoneal region. Orthologous to human ADGRV1 (adhesion G protein-coupled receptor V1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adgrv1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
familial febrile seizures 4 Alliance ?Febrile seizures, familial, 4 604352
Usher syndrome type 2C Alliance Usher syndrome, type 2C 605472
Usher syndrome type 2C Alliance Usher syndrome, type 2C, GPR98/PDZD7 digenic 605472
Associated With adgrv1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000203 GPS motif
Domain IPR003609 PAN/Apple domain
Domain IPR003644 Na-Ca exchanger/integrin-beta4
Domain IPR006558 LamG-like jellyroll fold
Domain IPR017981 GPCR, family 2-like
Family IPR000832 GPCR, family 2, secretin-like
Family IPR026919 Adhesion G-protein coupled receptor V1
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily IPR038081 CalX-like domain superfamily
Repeat IPR009039 EAR
Domain Details Per Protein
Protein Length Adhesion G-protein coupled receptor V1 CalX-like domain superfamily Concanavalin A-like lectin/glucanase domain superfamily EAR GPCR, family 2-like GPCR, family 2, secretin-like GPS motif LamG-like jellyroll fold Na-Ca exchanger/integrin-beta4 PAN/Apple domain
UniProtKB:F1QEZ1 6198
UniProtKB:Q6JAN0 6199
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-adgrv1 polyclonal Rabbit
  • IHC
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations