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ZFIN ID: ZDB-FIG-070219-34
Nair et al., 2007 - Requirements for Endothelin type-A receptors and Endothelin-1 signaling in the facial ectoderm for the patterning of skeletogenic neural crest cells in zebrafish. Development (Cambridge, England)   134(2):335-345 Full text @ Development
Anatomical Term:
Stage: Prim-15

Fig. 8 Edn1-deficient ectoderm recapitulates the suc/edn1-/-mutant phenotype. Whole-mount RNA in situ hybridizations (A,B) with immunohistochemistry for biotin-dextran (C,D). (A-C) Dorsolateral views. hand2 expression at 30 hpf (A) is lost in suc;edn1-/- mutants (B). (C) Wild-type embryos that receive ectoderm from suc;edn1-/- donors lose hand2 expression adjacent to the transplanted ectoderm (brown cells, arrow). (D) Transverse cryosection through the arches of the embryo in panel C show that donor cells are confined to ectoderm (arrow, brown cells).

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
hand2 WT standard conditions Prim-15 pharyngeal arch ISH
edn1tf216b/tf216b standard conditions Prim-15 Not Detected pharyngeal arch ISH
Antibody Labeling Details No data available
Phenotype Details No data available
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development