FIGURE

Fig. 6

ID

ZDB-FIG-060605-15

Publication

Gupta et al., 2006 - BMP signaling restricts hemato-vascular development from lateral mesoderm during somitogenesis

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Fig. 6

Both Lmo2+ and Gata1+ hematopoietic cells are restricted by BMP signaling. Representative embryos are shown that are either control (A,C,E,G) or derived from fertilized eggs injected with either I(lmo2:δBR)I (B,D) or I(gata1:δBR)I (F,H), and analyzed for gene expression by in situ hybridization. The markers tested are as indicted: (A,B) scl; (C,D) lmo2; (E,F) gata1; (G,H) flk1. Expression of both scl and lmo2 is enhanced by expression of the mutant receptor in Lmo2+ cells (arrowheads in B and D), while gata1 (the hematopoietic marker; arrowheads) but not flk1 (the endothelial marker; arrows) is enhanced when the receptor is expressed in Gata1+ cells (E-H). Views are flat-mounted dorsal, anterior towards the left (A-F) or lateral, anterior towards the left (G,H).

Expression Data

Genes:	gata1a kdrl lmo2 tal1
Fish:	AB/TU
Anatomical Term:	lateral mesoderm
Stage Range:	5-9 somites to 10-13 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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