ZFIN ID: ZDB-GENE-980526-501
Gene Name: T-cell acute lymphocytic leukemia 1
Gene Symbol: tal1
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: tal-1, scl/tal1, scl, zgc:85605 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 22 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits sequence-specific DNA binding activity; involved in several processes, including animal organ development, blood vessel morphogenesis, and positive regulation of endothelial cell  ...
GENE EXPRESSION
All Expression Data: 300 figures from 199 publications
Directly Submitted Expression Data: 6 figures (25 images) from Thisse et al., 2004 [MGC:85605]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
t21384 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 24 figures from 8 publications
    Observed in:
    DISEASE ASSOCIATED WITH tal1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    acute lymphocytic leukemia Leukemia, T-cell acute lymphocytic, somatic 613065
    DISEASE ASSOCIATED WITH tal1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process hemangioblast cell differentiation (more)
    Cellular Component nucleus (more)
    Molecular Function sequence-specific DNA binding (more)
    GO Terms (all 29)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR011598 (1)
  • InterPro:IPR036638 (1)
  • InterPro:IPR040238 (1)
  • PROSITE:PS50888 (1)
  • Pfam:PF00010 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ottdart00000001376 (1) 2510
    tal1-201 (1) 2643
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tal1
    MARKER RELATIONSHIPS
    tal1Contained in: [BAC] CH211-135J1 (1) (order this), DKEY-38N4 (1) (order this)
    [PAC] BUSM1-129I22 (1) (order this)
    tal1Encodes: [cDNA] MGC:85605 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213237 (1) 2655bp
    Genomic GenBank:BX322568 (1) 134716bp
    Select Tool
    Polypeptide UniProtKB:O93507 (1) 324aa
    Sequence Clusters UniGene:75812 (1)
    Sequence Information (all 23)
    OTHER tal1 GENE PAGES
  • Alliance (1)
  • Gene:30766 (1)
  • VEGA:OTTDARG00000001276 (1)
  • VEGA:OTTDARG00000010062 (1)
  • Ensembl(GRCz11):ENSDARG00000019930 (2)
  • ORTHOLOGY for tal1 (Chr: 22)
    CITATIONS (346)