ZFIN All Figures, Conner <i>et al.</i>, 2014

Fig. 1

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	ascl1a EGFP
Antibody:	Ab1-ascl1
Fish:	nt11Tg
Conditions:	physical alteration: anatomical structure chemical treatment: purpurogallin, physical alteration: anatomical structure
Anatomical Term:	Muller cell
Stage:	Adult

Expression / Labeling details

PHENOTYPE:

Fish:	nt11Tg
Condition:	chemical treatment: purpurogallin, physical alteration: anatomical structure
Observed In:	Muller cell
Stage:	Adult

Phenotype details

Fig. 2

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	ascl1a her4.3 her6 notch1a notch1b notch3 stat3
Antibody:	Ab1-glul
Fish:	AB kca3Tg; kca4Tg
Conditions:	chemical treatment: drug chemical treatment: purpurogallin, heat shock
Anatomical Terms:	Muller cell retina
Stage:	Adult

Expression / Labeling details

PHENOTYPE:

Fish:	AB slc45a2^b4/b4 kca3Tg; kca4Tg
Conditions:	chemical treatment: drug heat shock chemical treatment: purpurogallin, heat shock
Observed In:	Muller cell Notch signaling pathway retinal inner nuclear layer cell population proliferation
Stage:	Adult

Phenotype details

Fig. 3

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	AB
Condition:	chemical treatment: drug
Observed In:	retina apoptotic process
Stage:	Adult

Phenotype details

Fig. 4

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	ascl1a EGFP
Fish:	AB AB + MO1-ascl1a nt11Tg
Conditions:	chemical treatment: purpurogallin chemical treatment: drug
Knockdown Reagent:	MO1-ascl1a
Anatomical Terms:	Muller cell retinal inner nuclear layer
Stage:	Adult

Expression / Labeling details

PHENOTYPE:

Fish:	AB AB + MO1-ascl1a
Conditions:	chemical treatment: purpurogallin chemical treatment: drug
Knockdown Reagent:	MO1-ascl1a
Observed In:	Muller cell retinal inner nuclear layer cell population proliferation
Stage:	Adult

Phenotype details

Fig. 5

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	EGFP stat3
Antibody:	Ab3-stat3
Fish:	nt11Tg
Condition:	chemical treatment: drug
Anatomical Term:	Muller cell
Stage:	Adult

Expression / Labeling details

PHENOTYPE:

Fish:	nt11Tg
Condition:	chemical treatment: drug
Observed In:	Muller cell Muller cell cell surface receptor signaling pathway via JAK-STAT retinal inner nuclear layer cell population proliferation
Stage:	Adult

Phenotype details

Fig. 6

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	stat3 tnfa
Antibodies:	Ab1-tnfa Ab3-stat3
Fish:	slc45a2^b4/b4
Conditions:	chemical treatment: purpurogallin chemical treatment: drug physical alteration: anatomical structure
Anatomical Terms:	optic fiber layer retina retinal inner nuclear layer retinal outer plexiform layer
Stage:	Adult

Expression / Labeling details

PHENOTYPE:

Fish:	slc45a2^b4/b4
Conditions:	chemical treatment: purpurogallin chemical treatment: drug chemical treatment: drug physical alteration: anatomical structure
Observed In:	cell surface receptor signaling pathway via JAK-STAT Muller cell retinal inner nuclear layer cell population proliferation
Stage:	Adult

Phenotype details

Fig. 7

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	EGFP GFP
Fish:	slc45a2^b4/b4; nt11Tg slc45a2^b4/b4; rw021Tg
Conditions:	chemical treatment: drug physical alteration: anatomical structure
Anatomical Terms:	Muller cell retinal ganglion cell layer retinal inner nuclear layer retinal neural layer retinal outer nuclear layer
Stage:	Adult

Expression / Labeling details

PHENOTYPE:

Fish:	slc45a2^b4/b4; nt11Tg slc45a2^b4/b4; rw021Tg
Conditions:	chemical treatment: drug physical alteration: anatomical structure
Observed In:	Muller cell Muller cell apoptotic process retinal inner nuclear layer cell population proliferation
Stage:	Adult

Phenotype details

Fig. 8

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Gene:	EGFP
Fish:	nt11Tg
Conditions:	chemical treatment: drug chemical treatment: purpurogallin chemical treatment: pharmaceutical
Anatomical Term:	Muller cell
Stage:	Adult

Expression / Labeling details

PHENOTYPE:

Fish:	nt11Tg
Conditions:	chemical treatment: drug chemical treatment: purpurogallin chemical treatment: pharmaceutical
Observed In:	Muller cell retinal inner nuclear layer cell population proliferation
Stage:	Adult

Phenotype details

Fig. 9

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	EGFP GFP
Fish:	nl1Tg rw021Tg
Conditions:	chemical treatment: drug chemical treatment: purpurogallin chemical treatment: pharmaceutical
Anatomical Terms:	retinal ganglion cell layer retinal inner nuclear layer retinal outer nuclear layer
Stage:	Adult

Expression / Labeling details

PHENOTYPE:

Fish:	nl1Tg rw021Tg
Condition:	chemical treatment: purpurogallin
Observed In:	retinal inner nuclear layer cell population proliferation retinal inner nuclear layer neuron differentiation
Stage:	Adult

Phenotype details

Fig. 10

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Gene:	GFP
Fish:	rw021Tg
Condition:	chemical treatment: purpurogallin
Anatomical Term:	retinal inner nuclear layer
Stage:	Adult

Expression / Labeling details

PHENOTYPE:

Fish:	rw021Tg
Condition:	chemical treatment: purpurogallin
Observed In:	retina apoptotic process
Stage:	Adult

Phenotype details

Fig. 11

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	EGFP prkcaa
Antibodies:	Ab1-prkca Ab2-elavl Ab11-mapk zpr-1
Fish:	WT nl1Tg nt19Tg
Condition:	chemical treatment: purpurogallin
Anatomical Terms:	amacrine cell Muller cell ON-bipolar cell retinal bipolar neuron retinal cone cell retinal rod cell
Stage:	Adult

Expression / Labeling details

PHENOTYPE:

Fish:	WT
Condition:	chemical treatment: purpurogallin
Observed In:	retina neuron differentiation
Stage:	Adult

Phenotype details

Acknowledgments

Full text @ J. Neurosci.

Conner et al., 2014

ZDB-PUB-141024-4
PMID:25339752

Repressing Notch Signaling and Expressing TNFα Are Sufficient to Mimic Retinal Regeneration by Inducing Müller Glial Proliferation to Generate Committed Progenitor Cells

Conner et al., 2014 ZDB-PUB-141024-4 PMID:25339752

Repressing Notch Signaling and Expressing TNFα Are Sufficient to Mimic Retinal Regeneration by Inducing Müller Glial Proliferation to Generate Committed Progenitor Cells

Conner et al., 2014

ZDB-PUB-141024-4
PMID:25339752