Gene

her6

ID
ZDB-GENE-980526-144
Name
hairy-related 6
Symbol
her6 Nomenclature History
Previous Names
  • cb129 (1)
  • Hes1b (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including Notch signaling pathway; nervous system development; and somite specification. Predicted to localize to nucleus. Is expressed in several structures, including anterior neural keel; mesoderm; nervous system; neuronal stem cell; and pectoral fin. Orthologous to human HES1 (hes family bHLH transcription factor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
55 figures from 38 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Coolen et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With her6 Human Ortholog
No data available
Associated With her6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003650 Orange domain
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain Orange domain
UniProtKB:Q90468 334
UniProtKB:A0A2R8Q6M1 327
UniProtKB:Q6PBX3 270
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations