ZFIN ID: ZDB-FIG-150715-13
Conner et al., 2014 - Repressing Notch Signaling and Expressing TNFα Are Sufficient to Mimic Retinal Regeneration by Inducing Müller Glial Proliferation to Generate Committed Progenitor Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience   34(43):14403-19 Full text @ J. Neurosci.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Antibody:
Fish:
Conditions:
Anatomical Terms:
Stage: Adult
PHENOTYPE:
Fish:
Conditions:
Observed In:
Stage: Adult

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
ascl1a AB chemical treatment: drug Adult retina RTPCR
her4.3 AB chemical treatment: drug Adult retina RTPCR
her6 AB standard conditions Adult Muller cell ISH
AB chemical treatment: drug Adult Muller cell ISH
Adult retina RTPCR
notch1a AB standard conditions Adult Muller cell ISH
notch1b AB standard conditions Adult Muller cell ISH
notch3 AB standard conditions Adult Muller cell ISH
stat3 AB chemical treatment: drug Adult retina RTPCR
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Qualifier Anatomy
Ab1-glul IHC kca3Tg; kca4Tg heat shock, chemical treatment: purpurogallin Adult Not Detected Muller cell
Phenotype Details
Fish Conditions Stage Phenotype
AB chemical treatment: drug Adult Muller cell proliferative, abnormal
Adult Notch signaling pathway decreased occurrence, abnormal
Adult retinal inner nuclear layer cell population proliferation increased occurrence, abnormal
kca3Tg; kca4Tg heat shock Adult Muller cell proliferative, normal
kca3Tg; kca4Tg heat shock, chemical treatment: purpurogallin Adult Muller cell proliferative, normal
slc45a2b4/b4 heat shock, chemical treatment: purpurogallin Adult Muller cell proliferative, abnormal
Adult retinal inner nuclear layer cell population proliferation increased occurrence, abnormal
Full text @ J. Neurosci.