ZFIN

ZFIN ID: ZDB-TGCONSTRCT-090625-1

ZFIN ID: ZDB-TGCONSTRCT-090625-1

CITATIONS (140 total)

Transgenic Construct Name:	Tg(EPV.Tp1-Mmu.Hbb:EGFP)
Transgenic Construct Symbol:	Tg(EPV.Tp1-Mmu.Hbb:EGFP)

Barazzuol, L., Cieri, D., Facchinello, N., Calì, T., Washbourne, P., Argenton, F., Pizzo, P. (2023) Unraveling Presenilin 2 Functions in a Knockout Zebrafish Line to Shed Light into Alzheimer's Disease Pathogenesis. Cells. 12(3):

Mi, J., Liu, K.C., Andersson, O. (2023) Decoding pancreatic endocrine cell differentiation and β cell regeneration in zebrafish. Science advances. 9:eadf5142eadf5142

Ellis, J.L., Evason, K.J., Zhang, C., Fourman, M.N., Liu, J., Ninov, N., Delous, M., Vanhollebeke, B., Fiddes, I., Otis, J.P., Houvras, Y., Farber, S.A., Xu, X., Lin, X., Stainier, D.Y.R., Yin, C. (2022) A missense mutation in the proprotein convertase gene furinb causes hepatic cystogenesis during liver development in zebrafish. Hepatology communications. 6(11):3083-3097

Karampelias, C., Watt, K., Mattsson, C.L., Ruiz, Á.F., Rezanejad, H., Mi, J., Liu, X., Chu, L., Locasale, J.W., Korbutt, G.S., Rovira, M., Larsson, O., Andersson, O. (2022) MNK2 deficiency potentiates β-cell regeneration via translational regulation. Nature Chemical Biology. 18(9):942-953

Morales, R.A., Rabahi, S., Diaz, O.E., Salloum, Y., Kern, B.C., Westling, M., Luo, X., Parigi, S.M., Monasterio, G., Das, S., Hernández, P.P., Villablanca, E.J. (2022) Interleukin-10 regulates goblet cell numbers through Notch signaling in the developing zebrafish intestine. Mucosal immunology. 15(5):940-951

Potts, K.S., Cameron, R.C., Metidji, A., Ghazale, N., Wallace, L., Leal-Cervantes, A.I., Palumbo, R., Barajas, J.M., Gupta, V., Aluri, S., Pradhan, K., Myers, J.A., McKinstry, M., Bai, X., Choudhary, G.S., Shastri, A., Verma, A., Obeng, E.A., Bowman, T.V. (2022) Splicing factor deficits render hematopoietic stem and progenitor cells sensitive to STAT3 inhibition. Cell Reports. 41:111825111825

Qi, J., Rittershaus, A., Priya, R., Mansingh, S., Stainier, D.Y.R., Helker, C.S.M. (2022) Apelin signaling dependent endocardial protrusions promote cardiac trabeculation in zebrafish. eLIFE. 11:

Risato, G., Celeghin, R., Brañas Casas, R., Dinarello, A., Zuppardo, A., Vettori, A., Pilichou, K., Thiene, G., Basso, C., Argenton, F., Visentin, S., Cosmi, E., Tiso, N., Beffagna, G. (2022) Hyperactivation of Wnt/β-catenin and Jak/Stat3 pathways in human and zebrafish foetal growth restriction models: Implications for pharmacological rescue. Frontiers in cell and developmental biology. 10:943127

Sánchez-Iranzo, H., Halavatyi, A., Diz-Muñoz, A. (2022) Strength of interactions in the Notch gene regulatory network determines patterning and fate in the notochord. eLIFE. 11:

Vignes, H., Vagena-Pantoula, C., Prakash, M., Fukui, H., Norden, C., Mochizuki, N., Jug, F., Vermot, J. (2022) Extracellular mechanical forces drive endocardial cell volume decrease during zebrafish cardiac valve morphogenesis. Developmental Cell. 57(5):598-609.e5

Wada, Y., Tsukatani, H., Kuroda, C., Miyazaki, Y., Otoshi, M., Kobayashi, I. (2022) Jagged 2b induces intercellular signaling within somites to establish hematopoietic stem cell fate in zebrafish. Development (Cambridge, England). 149(7)

Zhao, C., Matalonga, J., Lancman, J.J., Liu, L., Xiao, C., Kumar, S., Gates, K.P., He, J., Graves, A., Huisken, J., Azuma, M., Lu, Z., Chen, C., Ding, B.S., Dong, P.D.S. (2022) Regenerative failure of intrahepatic biliary cells in Alagille syndrome rescued by elevated Jagged/Notch/Sox9 signaling. Proceedings of the National Academy of Sciences of the United States of America. 119:e2201097119e2201097119

Zhao, F., He, J., Tang, J., Cui, N., Shi, Y., Li, Z., Liu, S., Wang, Y., Ma, M., Zhao, C., Luo, L., Li, L. (2022) Brain milieu induces early microglial maturation through the BAX-Notch axis. Nature communications. 13:6117

Zhao, S., Feng, S., Tian, Y., Wen, Z. (2022) Hemogenic and aortic endothelium arise from a common hemogenic angioblast precursor and are specified by the Etv2 dosage. Proceedings of the National Academy of Sciences of the United States of America. 119:e2119051119e2119051119

Ghaffari, K., Pierce, L.X., Roufaeil, M., Gibson, I., Tae, K., Sahoo, S., Cantrell, J.R., Andersson, O., Lau, J., Sakaguchi, T.F. (2021) NCK-associated protein 1 like (nckap1l) minor splice variant regulates intrahepatic biliary network morphogenesis. PLoS Genetics. 17:e1009402

Karampelias, C., Rezanejad, H., Rosko, M., Duan, L., Lu, J., Pazzagli, L., Bertolino, P., Cesta, C.E., Liu, X., Korbutt, G.S., Andersson, O. (2021) Reinforcing one-carbon metabolism via folic acid/Folr1 promotes β-cell differentiation. Nature communications. 12:3362

Lam, W.Y., Tang, C.S., So, M.T., Yue, H., Hsu, J.S., Chung, P.H., Nicholls, J.M., Yeung, F., Lee, C.D., Ngo, D.N., Nguyen, P.A.H., Mitchison, H.M., Jenkins, D., O'Callaghan, C., Garcia-Barceló, M.M., Lee, S.L., Sham, P.C., Lui, V.C., Tam, P.K. (2021) Identification of a wide spectrum of ciliary gene mutations in nonsyndromic biliary atresia patients implicates ciliary dysfunction as a novel disease mechanism. EBioMedicine. 71:103530

Pham, D.H., Kudira, R., Xu, L., Valencia, C.A., Ellis, J.L., Shi, T., Evason, K.J., Osuji, I., Matuschek, N., Pfuher, L., Mullen, M., Mohanty, S.K., Husami, A., Bull, L.N., Zhang, K., Wali, S., Yin, C., Miethke, A. (2021) Deleterious variants in ABCC12 are detected in idiopathic chronic cholestasis and cause intrahepatic bile duct loss in model organisms: ABCC12 pathogenic variants lead to cholestasis. Gastroenterology. 161(1):287-300.e16

Rajan, S.G., Nacke, L.M., Dhingra, J.S., Saxena, A. (2021) Notch signaling mediates olfactory multiciliated cell specification. Cells & development. 168:203715

Schmitner, N., Recheis, C., Thönig, J., Kimmel, R.A. (2021) Differential Responses of Neural Retina Progenitor Populations to Chronic Hyperglycemia. Cells. 10(11):

Soto, R.A., Najia, M.A.T., Hachimi, M., Frame, J.M., Yette, G.A., Lummertz da Rocha, E., Stankunas, K., Daley, G.Q., North, T.E. (2021) Sequential regulation of hemogenic fate and hematopoietic stem and progenitor cell formation from arterial endothelium by Ezh1/2. Stem Cell Reports. 16(7):1718-1734

Templehof, H., Moshe, N., Avraham-Davidi, I., Yaniv, K. (2021) Zebrafish mutants provide insights into Apolipoprotein B functions during embryonic development and pathological conditions. JCI insight. 6(13):

Tsedeke, A.T., Allanki, S., Gentile, A., Jimenez-Amilburu, V., Rasouli, S.J., Guenther, S., Lai, S.L., Stainier, D.Y.R., Marín-Juez, R. (2021) Cardiomyocyte heterogeneity during zebrafish development and regeneration. Developmental Biology. 476:259-271

Zhao, C., Lancman, J.J., Yang, Y., Gates, K.P., Cao, D., Barske, L., Matalonga, J., Pan, X., He, J., Graves, A., Huisken, J., Chen, C., Dong, P.D.S. (2021) Intrahepatic cholangiocyte regeneration from an Fgf-dependent extrahepatic progenitor niche in a zebrafish model of Alagille Syndrome. Hepatology (Baltimore, Md.). 75(3):567-583

Chaturantabut, S., Shwartz, A., Garnaas, M.K., LaBella, K., Li, C.C., Carroll, K.J., Cutting, C.C., Budrow, N., Palaria, A., Gorelick, D.A., Tremblay, K.D., North, T.E., Goessling, W. (2020) Estrogen acts via estrogen receptor 2b to regulate hepatobiliary fate during vertebrate development. Hepatology (Baltimore, Md.). 72(5):1786-1799

Cheung, Y., Wu, Z., Garcia-Barcelo, M.M., Tam, P.K.H., Ma, A.C.H., Lui, V.C.H. (2020) Deletion of interleukin enhancer binding factor 2 (ILF2) resulted in defective biliary development and bile flow blockage. Journal of Pediatric Surgery. 56(2):352-359

da Silva, R.S., Dantas, V.L.G., Alves, L.U., Batissoco, A.C., Oiticica, J., Lawrence, E.A., Kawafi, A., Yang, Y., Nicastro, F.S., Novaes, B.C., Hammond, C., Kague, E., Netto, R.C.M. (2020) NCOA3 identified as a new candidate to explain autosomal dominant progressive hearing loss. Human molecular genetics. 29(22):3691-3705

Espanola, S.G., Song, H., Ryu, E., Saxena, A., Kim, E.S., Manegold, J.E., Nasamran, C.A., Sahoo, D., Oh, C.K., Bickers, C., Shin, U., Grainger, S., Park, Y.H., Pandolfo, L., Kang, M.S., Kang, S., Myung, K., Cooper, K.L., Yelon, D., Traver, D., Lee, Y. (2020) Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h. Nature cell biology. 22(12):1411-1422

Fish, J.E., Flores-Suarez, C.P., Boudreau, E., Herman, A.M., Gutierrez, M.C., Gustafson, D., DiStefano, P.V., Cui, M., Chen, Z., Berman De Ruiz, K., Schexnayder, T.S., Ward, C.S., Radovanovic, I., Wythe, J.D. (2020) Somatic Gain of KRAS Function in the Endothelium is Sufficient to Cause Vascular Malformations that Require MEK but not PI3K Signaling. Circulation research. 127(6):727-743

Freudenblum, J., Meyer, D., Kimmel, R.A. (2020) Inducible Mosaic Cell Labeling Provides Insights Into Pancreatic Islet Morphogenesis. Frontiers in cell and developmental biology. 8:586651

Guo, Y., Cheng, B.Y.L., Wang, D., Ma, A.C.H., He, B.L., Man, T.K., Cheung, M.P.L., Shi, X., Ng, N.K.L., Leung, A.Y.H. (2020) Function of Arl4aa in the Initiation of Hematopoiesis in Zebrafish by Maintaining Golgi Complex Integrity in Hemogenic Endothelium. Stem Cell Reports. 14(4):575-589

Male, I., Ozacar, A.T., Fagan, R.R., Loring, M.D., Loring, M.D., Shen, M.C., Pace, V.A., Devine, C.A., Lawson, G.E., Lutservitz, A., Karlstrom, R.O. (2020) Hedgehog signaling regulates neurogenesis in the larval and adult zebrafish hypothalamus. eNeuro. 7(6):

Min, J., Ningappa, M., So, J., Shin, D., Sindhi, R., Subramaniam, S. (2020) Systems Analysis of Biliary Atresia Through Integration of High-Throughput Biological Data. Frontiers in Physiology. 11:966

Niu, X., Subramanian, A., Hwang, T.H., Schilling, T.F., Galloway, J.L. (2020) Tendon Cell Regeneration Is Mediated by Attachment Site-Resident Progenitors and BMP Signaling. Current biology : CB. 30(17):3277-3292.e5

So, J., Ningappa, M., Glessner, J., Min, J., Ashokkumar, C., Ranganathan, S., Higgs, B.W., Li, D., Sun, Q., Schmitt, L., Biery, A.C., Dobrowolski, S., Trautz, C., Fuhrman, L., Schwartz, M.C., Klena, N.T., Fusco, J., Prasadan, K., Adenuga, M., Mohamed, N., Yan, Q., Chen, W., Horne, W., Dhawan, A., Sharif, K., Kelly, D., Squires, R.H., Gittes, G.K., Hakonarson, H., Morell, V., Lo, C., Subramaniam, S., Shin, D., Sindhi, R. (2020) Biliary-Atresia-Associated Mannosidase-1-Alpha-2 Gene Regulates Biliary and Ciliary Morphogenesis and Laterality. Frontiers in Physiology. 11:538701

Weeks, O., Bossé, G.D., Oderberg, I.M., Akle, S., Houvras, Y., Wrighton, P.J., LaBella, K., Iversen, I., Tavakoli, S., Adatto, I., Schwartz, A., Kloosterman, D., Tsomides, A., Charness, M.E., Peterson, R.T., Steinhauser, M.L., Fazeli, P.K., Goessling, W. (2020) Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood. The Journal of Clinical Investigation. 130(5):2252-2269

Ando, K., Wang, W., Peng, D., Chiba, A., Lagendijk, A., Barske, L., Crump, J.G., Stainier, D.Y.R., Lendahl, U., Koltowska, K., Hogan, B.M., Fukuhara, S., Mochizuki, N., Betsholtz, C. (2019) Peri-arterial specification of vascular mural cells from naïve mesenchyme requires Notch signaling. Development (Cambridge, England). 146(2):

DeRossi, C., Bambino, K., Morrison, J., Sakarin, I., Villacorta-Martin, C., Zhang, C., Ellis, J.L., Fiel, M.I., Ybanez, M., Lee, Y.A., Huang, K.L., Yin, C., Sakaguchi, T.F., Friedman, S.L., Villanueva, A., Chu, J. (2019) Mannose Phosphate Isomerase and Mannose Regulate Hepatic Stellate Cell Activation and Fibrosis in Zebrafish and Humans. Hepatology (Baltimore, Md.). 70(6):2107-2122

Duchemin, A.L., Vignes, H., Vermot, J. (2019) Mechanically activated Piezo channels modulate outflow tract valve development through the Yap1 and Klf2-Notch signaling axis. eLIFE. 8:

Hsu, J.J., Vedula, V., Baek, K.I., Chen, C., Chen, J., Chou, M.I., Lam, J., Subhedar, S., Wang, J., Ding, Y., Chang, C.C., Lee, J., Demer, L.L., Tintut, Y., Marsden, A.L., Hsiai, T.K. (2019) Contractile and hemodynamic forces coordinate Notch1b-mediated outflow tract valve formation. JCI insight. 5(10):

Huang, M., Zhu, F., Jiao, J., Wang, J., Zhang, Y. (2019) Exposure to acrylamide disrupts cardiomyocyte interactions during ventricular morphogenesis in zebrafish embryos. The Science of the total environment. 656:1337-1345

Lan, Y., Pan, H., Li, C., Banks, K.M., Sam, J., Ding, B., Elemento, O., Goll, M.G., Evans, T. (2019) TETs Regulate Proepicardial Cell Migration through Extracellular Matrix Organization during Zebrafish Cardiogenesis. Cell Reports. 26:720-732.e4

Lush, M.E., Diaz, D.C., Koenecke, N., Baek, S., Boldt, H., St Peter, M.K., Gaitan-Escudero, T., Romero-Carvajal, A., Busch-Nentwich, E.M., Perera, A.G., Hall, K.E., Peak, A., Haug, J.S., Piotrowski, T. (2019) scRNA-Seq reveals distinct stem cell populations that drive hair cell regeneration after loss of Fgf and Notch signaling. eLIFE. 8:

Rho, S.S., Kobayashi, I., Oguri-Nakamura, E., Ando, K., Fujiwara, M., Kamimura, N., Hirata, H., Iida, A., Iwai, Y., Mochizuki, N., Fukuhara, S. (2019) Rap1b Promotes Notch-Signal-Mediated Hematopoietic Stem Cell Development by Enhancing Integrin-Mediated Cell Adhesion. Developmental Cell. 49(5):681-696.e6

Serrano, M.L.A., Demarest, B.L., Tone-Pah-Hote, T., Tristani-Firouzi, M., Yost, H.J. (2019) Inhibition of Notch signaling rescues cardiovascular development in Kabuki Syndrome. PLoS Biology. 17:e3000087

Sharma, P., Saraswathy, V.M., Xiang, L., Fürthauer, M. (2019) Notch-mediated inhibition of neurogenesis is required for zebrafish spinal cord morphogenesis. Scientific Reports. 9:9958

Stanic, K., Reig, G., Wichmann, I.A., Opazo, J.C., Owen, G.I., Corvalán, A.H., Concha, M.L., Amigo, J.D. (2019) The Reprimo gene family member, reprimo-like (rprml), is required for blood development in embryonic zebrafish. Scientific Reports. 9:7131

Tie, R., Li, H., Cai, S., Liang, Z., Shan, W., Wang, B., Tan, Y., Zheng, W., Huang, H. (2019) Interleukin-6 signaling regulates hematopoietic stem cell emergence. Experimental & molecular medicine. 51:1-12

Wei, L., Al Oustah, A., Blader, P., Roussigné, M. (2019) Notch signaling restricts FGF pathway activation in parapineal cells to promote their collective migration. eLIFE. 8:

Ye, L., Mueller, O., Bagwell, J., Bagnat, M., Liddle, R.A., Rawls, J.F. (2019) High fat diet induces microbiota-dependent silencing of enteroendocrine cells. eLIFE. 8:

Yu, S., He, J. (2019) Stochastic cell-cycle entry and cell-state-dependent fate outputs of injury-reactivated tectal radial glia in zebrafish. eLIFE. 8

Abdul-Wajid, S., Demarest, B.L., Yost, H.J. (2018) Loss of embryonic neural crest derived cardiomyocytes causes adult onset hypertrophic cardiomyopathy in zebrafish. Nature communications. 9:4603

Bickers, C., Española, S.D., Grainger, S., Pouget, C., Traver, D. (2018) Zebrafish snai2 mutants fail to phenocopy morphant phenotypes. PLoS One. 13:e0202747

Freudenblum, J., Iglesias, J.A., Hermann, M., Walsen, T., Wilfinger, A., Meyer, D., Kimmel, R.A. (2018) In vivo imaging of emerging endocrine cells reveals a requirement for PI3K-regulated motility in pancreatic islet morphogenesis.. Development (Cambridge, England). 145(3)

Giuliodori, A., Beffagna, G., Marchetto, G., Fornetto, C., Vanzi, F., Toppo, S., Facchinello, N., Santimaria, M., Vettori, A., Rizzo, S., Della Barbera, M., Pilichou, K., Argenton, F., Thiene, G., Tiso, N., Basso, C. (2018) Loss of cardiac Wnt/β-catenin signalling in Desmoplakin-deficient AC8 zebrafish models is rescuable by genetic and pharmacological intervention. Cardiovascular research. 114(8):1082-1097

Lee, J., Vedula, V., Baek, K.I., Chen, J., Hsu, J.J., Ding, Y., Chang, C.C., Kang, H., Small, A., Fei, P., Chuong, C.M., Li, R., Demer, L., Packard, R.R.S., Marsden, A.L., Hsiai, T.K. (2018) Spatial and temporal variations in hemodynamic forces initiate cardiac trabeculation. JCI insight. 3(13):

Muralidharan, P., Sarmah, S., Marrs, J.A. (2018) Retinal Wnt signaling defect in a zebrafish fetal alcohol spectrum disorder model. PLoS One. 13:e0201659

Yao, Y., Sun, S., Wang, J., Fei, F., Dong, Z., Ke, A.W., He, R., Wang, L., Zhang, L., Ji, M.B., Li, Q., Yu, M., Shi, G.M., Fan, J., Gong, Z., Wang, X. (2018) Canonical Wnt signaling remodels lipid metabolism in zebrafish hepatocytes following Ras oncogenic insult. Cancer research. 78(19):5548-5560

Baek, K.I., Packard, R.R., Hsu, J.J., Saffari, A., Ma, Z., Luu, A.P., Pietersen, A., Yen, H., Ren, B., Ding, Y., Sioutas, C., Li, R., Hsiai, T.K. (2017) Ultrafine Particles Exposure Reveals the Importance of FOXO1/Notch Activation Complex for Vascular Regeneration. Antioxidants & redox signaling. 28(13):1209-1223

Chen, X., Gays, D., Milia, C., Santoro, M.M. (2017) Cilia Control Vascular Mural Cell Recruitment in Vertebrates. Cell Reports. 18:1033-1047

Delfino-Machín, M., Madelaine, R., Busolin, G., Nikaido, M., Colanesi, S., Camargo-Sosa, K., Law, E.W., Toppo, S., Blader, P., Tiso, N., Kelsh, R.N. (2017) Sox10 contributes to the balance of fate choice in dorsal root ganglion progenitors. PLoS One. 12:e0172947

Dimri, M., Bilogan, C., Pierce, L.X., Naegele, G., Vasanji, A., Gibson, I., McClendon, A., Tae, K., Sakaguchi, T.F. (2017) Three-dimensional structural analysis reveals a Cdk5-mediated kinase cascade regulating hepatic biliary network branching in zebrafish. Development (Cambridge, England). 144:2595-2605

Ellis, J.L., Bove, K.E., Schuetz, E.G., Leino, D., Valencia, C.A., Schuetz, J.D., Miethke, A., Yin, C. (2017) Zebrafish abcb11b mutant reveals novel strategies to restore bile excretion impaired by bile salt export pump deficiency. Hepatology (Baltimore, Md.). 67(4):1531-1545

Fish, J.E., Cantu Gutierrez, M., Dang, L.T., Khyzha, N., Chen, Z., Veitch, S., Cheng, H.S., Khor, M., Antounians, L., Njock, M.S., Boudreau, E., Herman, A.M., Rhyner, A.M., Ruiz, O.E., Eisenhoffer, G.T., Medina-Rivera, A., Wilson, M.D., Wythe, J.D. (2017) Dynamic regulation of VEGF-inducible genes by an ERK/ERG/p300 transcriptional network. Development (Cambridge, England). 144:2428-2444

Hasan, S.S., Tsaryk, R., Lange, M., Wisniewski, L., Moore, J.C., Lawson, N.D., Wojciechowska, K., Schnittler, H., Siekmann, A.F. (2017) Endothelial Notch signalling limits angiogenesis via control of artery formation. Nature cell biology. 19(8):928-940

Liu, K.C., Leuckx, G., Sakano, D., Seymour, P.A., Mattsson, C.L., Rautio, L., Staels, W., Verdonck, Y., Serup, P., Kume, S., Heimberg, H., Andersson, O. (2017) Inhibition of Cdk5 Promotes β-cell Differentiation from Ductal Progenitors. Diabetes. 67(1):58-70

Schmitner, N., Kohno, K., Meyer, D. (2017) ptf1a⁺ , ela3l^- cells are developmentally maintained progenitors for exocrine regeneration following extreme loss of acinar cells in zebrafish larvae.. Disease models & mechanisms. 10(3):307-321

So, J., Khaliq, M., Evason, K., Ninov, N., Martin, B.L., Stainier, D.Y.R., Shin, D. (2017) Wnt/β-catenin signaling controls intrahepatic biliary network formation in zebrafish by regulating Notch activity. Hepatology (Baltimore, Md.). 67(6):2352-2366

Yang, Q., Yan, C., Yin, C., Gong, Z. (2017) Serotonin Activated Hepatic Stellate Cells Contribute to Sex Disparity in Hepatocellular Carcinoma. Cellular and molecular gastroenterology and hepatology. 3:484-499

Zhang, D., Gates, K.P., Barske, L., Wang, G., Lancman, J.J., Zeng, X.I., Groff, M., Wang, K., Parsons, M.J., Crump, J.G., Dong, P.D.S. (2017) Endoderm Jagged induces liver and pancreas duct lineage in zebrafish. Nature communications. 8:769

Daakour, S., Hajingabo, L.J., Kerselidou, D., Devresse, A., Kettmann, R., Simonis, N., Dequiedt, F., Twizere, J.C. (2016) Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor. BMC cancer. 16:335

De La Garza, A., Cameron, R.C., Nik, S., Payne, S.G., Bowman, T.V. (2016) The Spliceosomal Component Sf3b1 is Essential for Hematopoietic Differentiation in Zebrafish. Experimental hematology. 44(9):826-837.e4

Han, P., Bloomekatz, J., Ren, J., Zhang, R., Grinstein, J.D., Zhao, L., Burns, C.G., Burns, C.E., Anderson, R.M., Chi, N.C. (2016) Coordinating cardiomyocyte interactions to direct ventricular chamber morphogenesis. Nature. 534:700-4

Huang, W., Beer, R.L., Delaspre, F., Wang, G., Edelman, H.E., Park, H., Azuma, M., Parsons, M.J. (2016) Sox9b is a mediator of retinoic acid signaling restricting endocrine progenitor differentiation. Developmental Biology. 418(1):28-39

Koenig, A.L., Baltrunaite, K., Bower, N.I., Rossi, A., Stainier, D.Y., Hogan, B.M., Sumanas, S. (2016) Vegfa signaling promotes zebrafish intestinal vasculature development through endothelial cell migration from the posterior cardinal vein. Developmental Biology. 411(1):115-27

Lee, J., Fei, P., Packard, R.R., Kang, H., Xu, H., Baek, K.I., Jen, N., Chen, J., Yen, H., Kuo, C.J., Chi, N.C., Ho, C.M., Li, R., Hsiai, T.K. (2016) 4-Dimensional light-sheet microscopy to elucidate shear stress modulation of cardiac trabeculation. The Journal of Clinical Investigation. 126(5):1679-90

Liu, L.Y., Alexa, K., Cortes, M., Schatzman-Bone, S., Kim, A.J., Mukhopadhyay, B., Cinar, R., Kunos, G., North, T.E., Goessling, W. (2016) Cannabinoid receptor signaling regulates liver development and metabolism. Development (Cambridge, England). 143:609-22

Mouillesseaux, K.P., Wiley, D.S., Saunders, L.M., Wylie, L.A., Kushner, E.J., Chong, D.C., Citrin, K.M., Barber, A.T., Park, Y., Kim, J.D., Samsa, L.A., Kim, J., Liu, J., Jin, S.W., Bautch, V.L. (2016) Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6.. Nature communications. 7:13247

Yang, Q., Liu, X., Zhou, T., Cook, J., Nguyen, K., Bai, X. (2016) RNA polymerase II pausing differentially regulates signaling pathway genes to control hematopoietic stem cell emergence in zebrafish. Blood. 128(13):1701-10

Zhao, X., Lorent, K., Wilkins, B., Marchione, D.M., Gillespie, K., Waisbourd-Zinman, O., So, J., Koo, K.A., Shin, D., Porter, J.R., Wells, R.G., Blair, I., Pack, M. (2016) Glutathione antioxidant pathway activity and reserve determine toxicity and specificity of the biliary toxin biliatresone in zebrafish. Hepatology (Baltimore, Md.). 64(3):894-907

Cortes, M., Liu, S.Y., Kwan, W., Alexa, K., Goessling, W., North, T.E. (2015) Accumulation of the Vitamin D Precursor Cholecalciferol Antagonizes Hedgehog Signaling to Impair Hemogenic Endothelium Formation. Stem Cell Reports. 5:471-9

Coxam, B., Neyt, C., Grassini, D.R., Le Guen, L., Smith, K.A., Schulte-Merker, S., Hogan, B.M. (2015) carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (cad) regulates Notch signaling and vascular development in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 244(1):1-9

Delaspre, F., Beer, R.L., Rovira, M., Huang, W., Wang, G., Gee, S., Vitery, M.D., Wheelan, S.J., Parsons, M.J. (2015) Centroacinar cells are progenitors that contribute to endocrine pancreas regeneration. Diabetes. 64(10):3499-509

Ghaye, A.P., Bergemann, D., Tarifeño-Saldivia, E., Flasse, L.C., Von Berg, V., Peers, B., Voz, M.L., Manfroid, I. (2015) Progenitor potential of nkx6.1-expressing cells throughout zebrafish life and during beta cell regeneration. BMC Biology. 13:70

Hen, G., Nicenboim, J., Mayseless, O., Asaf, L., Shin, M., Busolin, G., Hofi, R., Almog, G., Tiso, N., Lawson, N.D., Yaniv, K. (2015) Venous-derived angioblasts generate organ-specific vessels during embryonic development. Development (Cambridge, England). 142(24):4266-78

Kaufman, R., Weiss, O., Sebbagh, M., Ravid, R., Gibbs-Bar, L., Yaniv, K., Inbal, A. (2015) Development and origins of Zebrafish ocular vasculature. BMC Developmental Biology. 15:18

Khaliq, M., Choi, T.Y., So, J., Shin, D. (2015) Id2a is required for hepatic outgrowth during liver development in zebrafish. Mechanisms of Development. 138 Pt 3:399-414

Li, C., Lan, Y., Schwartz-Orbach, L., Korol, E., Tahiliani, M., Evans, T., Goll, M.G. (2015) Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence. Cell Reports. 12(7):1133-43

Lin, M.I., Price, E.N., Boatman, S., Hagedorn, E.J., Trompouki, E., Satishchandran, S., Carspecken, C.W., Uong, A., DiBiase, A., Yang, S., Canver, M.C., Dahlberg, A., Lu, Z., Zhang, C.C., Orkin, S.H., Bernstein, I.D., Aster, J.C., White, R.M., Zon, L.I. (2015) Angiopoietin-like proteins stimulate HSPC development through interaction with Notch receptor signaling. eLIFE. 4

Ningappa, M., So, J., Glessner, J., Ashokkumar, C., Ranganathan, S., Min, J., Higgs, B.W., Sun, Q., Haberman, K., Schmitt, L., Vilarinho, S., Mistry, P.K., Vockley, G., Dhawan, A., Gittes, G.K., Hakonarson, H., Jaffe, R., Subramaniam, S., Shin, D., Sindhi, R. (2015) The Role of ARF6 in Biliary Atresia. PLoS One. 10:e0138381

Olena, A.F., Rao, M.B., Thatcher, E.J., Wu, S.Y., Patton, J.G. (2015) miR-216a regulates snx5, a novel notch signaling pathway component, during zebrafish retinal development. Developmental Biology. 400(1):72-81

Pandey, R., Botros, M.A., Nacev, B.A., Albig, A.R. (2015) Cyclosporin A Disrupts Notch Signaling and Vascular Lumen Maintenance. PLoS One. 10:e0119279

Rochon, E.R., Wright, D.S., Schubert, M.M., Roman, B.L. (2015) Context-specific interactions between Notch and ALK1 cannot explain ALK1-associated arteriovenous malformations. Cardiovascular research. 107(1):143-52

Samsa, L.A., Givens, C., Tzima, E., Stainier, D.Y., Qian, L., Liu, J. (2015) Cardiac contraction activates endocardial Notch signaling to modulate chamber maturation in zebrafish. Development (Cambridge, England). 142:4080-91

Zancan, I., Bellesso, S., Costa, R., Salvalaio, M., Stroppiano, M., Hammond, C., Argenton, F., Filocamo, M., Moro, E. (2015) Glucocerebrosidase deficiency in zebrafish affects primary bone ossification through increased oxidative stress and reduced Wnt/β-catenin signaling. Human molecular genetics. 24(5):1280-94

Carroll, K.J., Esain, V., Garnaas, M.K., Cortes, M., Dovey, M.C., Nissim, S., Frechette, G.M., Liu, S.Y., Kwan, W., Cutting, C.C., Harris, J.M., Gorelick, D.A., Halpern, M.E., Lawson, N.D., Goessling, W., North, T.E. (2014) Estrogen defines the dorsal-ventral limit of VEGF regulation to specify the location of the hemogenic endothelial niche. Developmental Cell. 29:437-53

Espín-Palazón, R., Stachura, D.L., Campbell, C.A., García-Moreno, D., Del Cid, N., Kim, A.D., Candel, S., Meseguer, J., Mulero, V., Traver, D. (2014) Proinflammatory signaling regulates hematopoietic stem cell emergence. Cell. 159:1070-85

Feng, L., Jiang, H., Wu, P., Marlow, F.L. (2014) Negative feedback regulation of Wnt signaling via N-linked fucosylation in zebrafish. Developmental Biology. 395(2):268-86

Fischer, B., Metzger, M., Richardson, R., Knyphausen, P., Ramezani, T., Franzen, R., Schmelzer, E., Bloch, W., Carney, T.J., and Hammerschmidt, M. (2014) p53 and TAp63 promote keratinocyte proliferation and differentiation in breeding tubercles of the zebrafish. PLoS Genetics. 10(1):e1004048

He, J., Lu, H., Zou, Q., and Luo, L. (2014) Regeneration of Liver After Extreme Hepatocyte Loss Occurs Mainly via Biliary Transdifferentiation in Zebrafish. Gastroenterology. 146(3):789-800.e8

Huang, M., Chang, A., Choi, M., Zhou, D., Anania, F.A., Shin, C.H. (2014) Antagonistic interaction between Wnt and Notch activity modulates the regenerative capacity of a zebrafish fibrotic liver model. Hepatology (Baltimore, Md.). 60(5):1753-66

Kobayashi, I., Kobayashi-Sun, J., Kim, A.D., Pouget, C., Fujita, N., Suda, T., Traver, D. (2014) Jam1a-Jam2a interactions regulate haematopoietic stem cell fate through Notch signalling. Nature. 512(7514):319-23

Kobia, F., Duchi, S., Deflorian, G., and Vaccari, T. (2014) Pharmacologic inhibition of vacuolar H+ ATPase reduces physiologic and oncogenic Notch signaling. Molecular Oncology. 8(2):207-20

Leitch, C.C., Lodh, S., Prieto-Echagüe, V., Badano, J.L., Zaghloul, N.A. (2014) Basal body proteins regulate Notch signaling via endosomal trafficking. Journal of Cell Science. 127(Pt 11):2407-19

Quillien, A., Moore, J.C., Shin, M., Siekmann, A.F., Smith, T., Pan, L., Moens, C.B., Parsons, M.J., Lawson, N.D. (2014) Distinct Notch signaling outputs pattern the developing arterial system. Development (Cambridge, England). 141:1544-52

Subedi, A., Macurak, M., Gee, S.T., Monge, E., Goll, M.G., Potter, C.J., Parsons, M.J., and Halpern, M.E. (2014) Adoption of the Q transcriptional regulatory system for zebrafish transgenesis. Methods (San Diego, Calif.). 66(3):433-40

Wilkins, B.J., Gong, W., and Pack, M. (2014) A novel keratin18 promoter that drives reporter gene expression in the intrahepatic and extrahepatic biliary system allows isolation of cell-type specific transcripts from zebrafish liver. Gene expression patterns : GEP. 14(2):62-68

Zhang, D., Golubkov, V.S., Han, W., Correa, R.G., Zhou, Y., Lee, S., Strongin, A.Y., Dong, P.D. (2014) Identification of Annexin A4 as a hepatopancreas factor involved in liver cell survival. Developmental Biology. 395(1):96-110

Alghisi, E., Distel, M., Malagola, M., Anelli, V., Santoriello, C., Herwig, L., Krudewig, A., Henkel, C.V., Russo, D., and Mione, M.C. (2013) Targeting oncogene expression to endothelial cells induces proliferation of the myelo-erythroid lineage by repressing the notch pathway. Leukemia. 24(6):943-53

Bosco, A., Bureau, C., Affaticati, P., Gaspar, P., Bally-Cuif, L., and Lillesaar, C. (2013) Development of hypothalamic serotoninergic neurons requires Fgf signalling via the ETS-domain transcription factor Etv5b. Development (Cambridge, England). 140(2):372-384

Corallo, D., Schiavinato, A., Trapani, V., Moro, E., Argenton, F., and Bonaldo, P. (2013) Emilin3 is required for notochord sheath integrity and interacts with Scube2 to regulate notochord-derived Hedgehog signals. Development (Cambridge, England). 140(22):4594-4601

Luxan, G., Casanova, J.C., Martinez-Poveda, B., Prados, B., D'Amato, G., Macgrogan, D., Gonzalez-Rajal, A., Dobarro, D., Torroja, C., Martinez, F., Izquierdo-García, J.L., Fernandez-Friera, L., Sabater-Molina, M., Kong, Y.Y., Pizarro, G., Ibañez, B., Medrano, C., García-Pavía, P., Gimeno, J.R., Monserrat, L., Jimenez-Borreguero, L.J., and de la Pompa, J.L. (2013) Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy. Nature medicine. 19(2):193-201

Matsuda, H., Parsons, M.J., and Leach, S.D. (2013) Aldh1-expressing endocrine progenitor cells regulate secondary islet formation in larval zebrafish pancreas. PLoS One. 8(9):e74350

Nussbaum, J.M., Liu, L.J., Hasan, S.A., Schaub, M., McClendon, A., Stainier, D.Y., and Sakaguchi, T.F. (2013) Homeostatic generation of reactive oxygen species protects the zebrafish liver from steatosis. Hepatology (Baltimore, Md.). 58(4):1326-1338

Wilkins, B.J., and Pack, M. (2013) Zebrafish models of human liver development and disease. Comprehensive Physiology. 3(3):1213-1230

Wilkins, B.J., Lorent, K., Matthews, R.P., and Pack, M. (2013) p53-Mediated Biliary Defects Caused by Knockdown of cirh1a, the Zebrafish Homolog of the Gene Responsible for North American Indian Childhood Cirrhosis. PLoS One. 8(10):e77670

Wythe, J.D., Dang, L.T., Devine, W.P., Boudreau, E., Artap, S.T., He, D., Schachterle, W., Stainier, D.Y., Oettgen, P., Black, B.L., Bruneau, B.G., and Fish, J.E. (2013) ETS Factors Regulate Vegf-Dependent Arterial Specification. Developmental Cell. 26(1):45-58

Zhang, R., Han, P., Yang, H., Ouyang, K., Lee, D., Lin, Y.F., Ocorr, K., Kang, G., Chen, J., Stainier, D.Y., Yelon, D., and Chi, N.C. (2013) In vivo cardiac reprogramming contributes to zebrafish heart regeneration. Nature. 498(7455):497-501

Cheung, I.D., Bagnat, M., Ma, T.P., Datta, A., Evason, K., Moore, J.C., Lawson, N.D., Mostov, K.E., Moens, C.B., and Stainier, D.Y. (2012) Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b. Developmental Biology. 361(1):68-78

Delous, M., Yin, C., Shin, D., Ninov, N., Debrito Carten, J., Pan, L., Ma, T.P., Farber, S.A., Moens, C.B., and Stainier, D.Y. (2012) sox9b Is a Key Regulator of Pancreaticobiliary Ductal System Development. PLoS Genetics. 8(6):e1002754

Garnaas, M.K., Cutting, C.C., Meyers, A., Kelsey, P.B., Harris, J.M., North, T.E., and Goessling, W. (2012) Rargb regulates organ laterality in a zebrafish model of right atrial isomerism. Developmental Biology. 372(2):178-189

Ninov, N., Borius, M., and Stainier, D.Y. (2012) Different levels of Notch signaling regulate quiescence, renewal and differentiation in pancreatic endocrine progenitors. Development (Cambridge, England). 139(9):1557-1567

Schaub, M., Nussbaum, J., Verkade, H., Ober, E.A., Stainier, D.Y., and Sakaguchi, T.F. (2012) Mutation of zebrafish Snapc4 is associated with loss of the intrahepatic biliary network. Developmental Biology. 363(1):128-137

Walker, S.L., Ariga, J., Mathias, J.R., Coothankandaswamy, V., Xie, X., Distel, M., Köster, R.W., Parsons, M.J., Bhalla, K.N., Saxena, M.T., and Mumm, J.S. (2012) Automated reporter quantification in vivo: high-throughput screening method for reporter-based assays in zebrafish. PLoS One. 7(1):e29916

Clements, W.K., Kim, A.D., Ong, K.G., Moore, J.C., Lawson, N.D., and Traver, D. (2011) A somitic Wnt16/Notch pathway specifies haematopoietic stem cells. Nature. 474(7350):220-224

Quillien, A., Blanco-Sanchez, B., Halluin, C., Moore, J.C., Lawson, N.D., Blader, P., and Cau, E. (2011) BMP signaling orchestrates photoreceptor specification in the zebrafish pineal gland in collaboration with Notch. Development (Cambridge, England). 138(11):2293-2302

Rovira, M., Huang, W., Yusuff, S., Shim, J.S., Ferrante, A.A., Liu, J.O., and Parsons, M.J. (2011) Chemical screen identifies FDA-approved drugs and target pathways that induce precocious pancreatic endocrine differentiation. Proceedings of the National Academy of Sciences of the United States of America. 108(48):19264-9

Wang, Y., Rovira, M., Yusuff, S., and Parsons, M.J. (2011) Genetic inducible fate mapping in larval zebrafish reveals origins of adult insulin-producing {beta}-cells. Development (Cambridge, England). 138(4):609-617

Zygmunt, T., Gay, C.M., Blondelle, J., Singh, M.K., Flaherty, K.M., Means, P.C., Herwig, L., Krudewig, A., Belting, H.G., Affolter, M., Epstein, J.A., and Torres-Vazquez, J. (2011) Semaphorin-PlexinD1 Signaling Limits Angiogenic Potential via the VEGF Decoy Receptor sFlt1. Developmental Cell. 21(2):301-314

Chapouton, P., Skupien, P., Hesl, B., Coolen, M., Moore, J.C., Madelaine, R., Kremmer, E., Faus-Kessler, T., Blader, P., Lawson, N.D., and Bally-Cuif, L. (2010) Notch activity levels control the balance between quiescence and recruitment of adult neural stem cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30(23):7961-7974

Geudens, I., Herpers, R., Hermans, K., Segura, I., Ruiz de Almodovar, C., Bussmann, J., De Smet, F., Vandevelde, W., Hogan, B.M., Siekmann, A., Claes, F., Moore, J.C., Pistocchi, A.S., Loges, S., Mazzone, M., Mariggi, G., Bruyere, F., Cotelli, F., Kerjaschki, D., Noel, A., Foidart, J.M., Gerhardt, H., Ny, A., Langenberg, T., Lawson, N.D., Duckers, H.J., Schulte-Merker, S., Carmeliet, P., and Dewerchin, M. (2010) Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish. Arterioscler. Thromb. Vasc. Biol.. 30(9):1695-1702

Lorent, K., Moore, J.C., Siekmann, A.F., Lawson, N., and Pack, M. (2010) Reiterative use of the notch signal during zebrafish intrahepatic biliary development. Developmental Dynamics : an official publication of the American Association of Anatomists. 239(3):855-864

Nicoli, S., Standley, C., Walker, P., Hurlstone, A., Fogarty, K.E., and Lawson, N.D. (2010) MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis. Nature. 464(7292):1196-1200

Parsons, M.J., Pisharath, H., Yusuff, S., Moore, J.C., Siekmann, A.F., Lawson, N., and Leach, S.D. (2009) Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas. Mechanisms of Development. 126(10):898-912

Additional Citations (6):

ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.

ZIRC and ZFIN staff (2013) Mutant and Transgenic Line Submissions 2013. ZFIN Direct Data Submission.

ZIRC and ZFIN staff (2009) Mutant and Transgenic Line Submissions 2009. ZFIN Direct Data Submission.

ZIRC and ZFIN Staff (2008) Mutant and Transgenic Line Submissions 2008. ZFIN Direct Data Submission.

Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.