ZFIN ID: ZDB-GENE-980526-79
CITATIONS (63 total)
Gene Name: hemoglobin, alpha adult 1
Gene Symbol: hbaa1
Wang, H., Siren, J., Perttunen, S., Immonen, K., Chen, Y.C., Narumanchi, S., Kosonen, R., Paavola, J., Laine, M., Tikkanen, I., Lakkisto, P. (2024) Deficiency of heme oxygenase 1a causes detrimental effects on cardiac function. Journal of Cellular and Molecular Medicine. 28:e18243e18243
Xie, L., Tao, Y., Shen, Z., Deng, H., Duan, X., Xue, Y., Chen, D., Li, Y. (2023) Congenital asplenia impairs heme-iron recycling during erythropoiesis in zebrafish. Developmental and comparative immunology. 151:105108
Morrison, J.K., DeRossi, C., Alter, I.L., Nayar, S., Giri, M., Zhang, C., Cho, J.H., Chu, J. (2022) Single-cell transcriptomics reveals conserved cell identities and fibrogenic phenotypes in zebrafish and human liver. Hepatology communications. 6(7):1711-1724
Qian, P., Kang, J., Liu, D., Xie, G. (2022) Single Cell Transcriptome Sequencing of Zebrafish Testis Revealed Novel Spermatogenesis Marker Genes and Stronger Leydig-Germ Cell Paracrine Interactions. Frontiers in genetics. 13:851719
Ragsdale, A., Ortega-Recalde, O., Dutoit, L., Besson, A.A., Chia, J.H.Z., King, T., Nakagawa, S., Hickey, A., Gemmell, N.J., Hore, T., Johnson, S.L. (2022) Paternal hypoxia exposure primes offspring for increased hypoxia resistance. BMC Biology. 20:185
Belmonte, R.L., Engbretson, I.L., Kim, J.H., Cajias, I., Ahn, E.E., Stachura, D.L. (2021) son is necessary for proper vertebrate blood development. PLoS One. 16:e0247489
Kim, S.H., Yang, D., Bae, Y.A. (2021) Hypoxic and nitrosative stress conditions modulate expression of myoglobin genes in a carcinogenic hepatobiliary trematode, Clonorchis sinensis. PLoS neglected tropical diseases. 15:e0009811
Niksirat, H., Siino, V., Steinbach, C., Levander, F. (2021) High-Resolution Proteomic Profiling Shows Sexual Dimorphism in Zebrafish Heart-Associated Proteins. Journal of Proteome Research. 20(8):4075-4088
Petrova, N.V., Klimenko, N.S., Kovina, A.P., Ioudinkova, E.S., Gavrilov, A.A., Iarovaia, O.V., Razin, S.V. (2020) Mechanisms mediating suppression of globin gene transcription in Danio rerio nonerythroid cells. Biochimie. 181:96-99
Wang, Y., Liu, X., Xie, B., Yuan, H., Zhang, Y., Zhu, J. (2019) The NOTCH1-dependent HIF1α/VGLL4/IRF2BP2 oxygen sensing pathway triggers erythropoiesis terminal differentiation. Redox Biology. 28:101313
Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
Eb-Levadoux, Y., Frelon, S., Simon, O., Arnaudguilhem, C., Lobinski, R., Mounicou, S. (2017) In vivo identification of potential uranium protein targets in zebrafish ovaries after chronic waterborne exposure. Metallomics : integrated biometal science. 9(5):525-534
Kovina, A.P., Petrova, N.V., Gushchanskaya, E.S., Dolgushin, K.V., Gerasimov, E.S., Galitsyna, A.A., Penin, A.A., Flyamer, I.M., Ioudinkova, E.S., Gavrilov, A.A., Vassetzky, Y.S., Ulianov, S.V., Iarovaia, O.V., Razin, S.V. (2017) Evolution of the genome 3D organization: comparison of fused and segregated globin gene clusters. Molecular Biology and Evolution. 34(6):1492-1504
Kulkeaw, K., Inoue, T., Ishitani, T., Nakanishi, Y., Zon, L.I., Sugiyama, D. (2017) Purification of zebrafish erythrocytes as a means of identifying a novel regulator of haematopoiesis. British journal of haematology. 180(3):420-431
Corti, P., Xue, J., Tejero, J., Wajih, N., Sun, M., Stolz, D.B., Tsang, M., Kim-Shapiro, D.B., Gladwin, M.T. (2016) Globin X is a six-coordinate globin that reduces nitrite to nitric oxide in fish red blood cells. Proceedings of the National Academy of Sciences of the United States of America. 113:8538-43
Krjutškov, K., Koel, M., Roost, A.M., Katayama, S., Einarsdottir, E., Jouhilahti, E.M., Söderhäll, C., Jaakma, Ü., Plaas, M., Vesterlund, L., Lohi, H., Salumets, A., Kere, J. (2016) Globin mRNA reduction for whole-blood transcriptome sequencing. Scientific Reports. 6:31584
Lin, K.H., Ho, Y.H., Chiang, J.C., Li, M.W., Lin, S.H., Chen, W.M., Chiang, C.L., Lin, Y.N., Yang, Y.J., Chen, C.N., Lu, J., Huang, C.J., Tigyi, G., Yao, C.L., Lee, H. (2016) Pharmacological activation of lysophosphatidic acid receptors regulates erythropoiesis. Scientific Reports. 6:27050
Lin, K.R., Yang-Yen, H.F., Lien, H.W., Liao, W.H., Huang, C.J., Lin, L.I., Li, C.L., Yen, J.J. (2016) Murine tribbles homolog 2 deficiency affects erythroid progenitor development and confers macrocytic anemia on mice. Scientific Reports. 6:31444
Nefedochkina, A.V., Petrova, N.V., Ioudinkova, E.S., Kovina, A.P., Iarovaia, O.V., Razin, S.V. (2016) Characterization of the enhancer element of the Danio rerio minor globin gene locus. Histochemistry and cell biology. 145(4):463-73
Svoboda, O., Stachura, D.L., Machonova, O., Zon, L.I., Traver, D., Bartunek, P. (2016) Ex vivo tools for the clonal analysis of zebrafish hematopoiesis. Nature Protocols. 11:1007-1020
Mercurio, S., Petrillo, S., Chiabrando, D., Bassi, Z.I., Gays, D., Camporeale, A., Vacaru, A., Miniscalco, B., Valperga, G., Silengo, L., Altruda, F., Baron, M.H., Santoro, M.M., Tolosano, E. (2015) The Heme Exporter Flvcr1 Regulates Expansion And Differentiation Of Committed Erythroid Progenitors By Controlling Intracellular Heme Accumulation. Haematologica. 100(6):720-9
Nolte, H., Konzer, A., Ruhs, A., Jungblut, B., Braun, T., Krüger, M. (2014) Global protein expression profiling of zebrafish organs based on in vivo incorporation of stable isotopes. Journal of Proteome Research. 13:2162-74
Svoboda, O., Stachura, D.L., Machonova, O., Pajer, P., Brynda, J., Zon, L.I., Traver, D., Bartunek, P. (2014) Dissection of vertebrate hematopoiesis using zebrafish thrombopoietin. Blood. 124(2):220-8
Almeida, D.V., Bianchini, A., and Marins, L.F. (2013) Growth hormone overexpression generates an unfavorable phenotype in juvenile transgenic zebrafish under hypoxic conditions. General and comparative endocrinology. 194C:102-109
Chen, K., Cole, R.B., and Rees, B.B. (2013) Hypoxia-induced changes in the zebrafish (Danio rerio) skeletal muscle proteome. Journal of proteomics. 78:477-485
Hess, I., Iwanami, N., Schorpp, M., and Boehm, T. (2013) Zebrafish model for allogeneic hematopoietic cell transplantation not requiring preconditioning. Proceedings of the National Academy of Sciences of the United States of America. 110(11):4327-32
Zhang, Z., Jia, H., Zhang, Q., Wan, Y., Zhou, Y., Jia, Q., Zhang, W., Yuan, W., Cheng, T., Zhu, X., and Fang, X. (2013) Assessment of hematopoietic failure due to Rpl11 deficiency in a zebrafish model of Diamond-Blackfan anemia by deep sequencing. BMC Genomics. 14:896
Ganis, J.J., Hsia, N., Trompouki, E., de Jong, J.L., Dibiase, A., Lambert, J.S., Jia, Z., Sabo, P.J., Weaver, M., Sandstrom, R., Stamatoyannopoulos, J.A., Zhou, Y., and Zon, L.I. (2012) Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR. Developmental Biology. 366(2):185-194
Nishiyama, T., Kaneda, R., Ono, T., Tohyama, S., Hashimoto, H., Endo, J., Tsuruta, H., Yuasa, S., Ieda, M., Makino, S., and Fukuda, K. (2012) miR-142-3p is essential for hematopoiesis and affects cardiac cell fate in zebrafish. Biochemical and Biophysical Research Communications. 425(4):755-761
Guan, B., Ma, H., Wang, Y., Hu, Y., Lin, Z., Zhu, Z., and Hu, W. (2011) Vitreoscilla Hemoglobin (VHb) Overexpression Increases Hypoxia Tolerance in Zebrafish (Danio rerio). Marine biotechnology (New York, N.Y.). 13(2):336-44
Tiedke, J., Gerlach, F., Mitz, S.A., Hankeln, T., and Burmester, T. (2011) Ontogeny of globin expression in zebrafish (Danio rerio). Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. 181(8):1011-21
Kulkeaw, K., Ishitani, T., Kanemaru, T., Fucharoen, S., and Sugiyama, D. (2010) Cold exposure down-regulates zebrafish hematopoiesis. Biochemical and Biophysical Research Communications. 394(4):859-864
Singh, S.K., Sundaram, C.S., Shanbhag, S., and Idris, M.M. (2010) Proteomic profile of zebrafish brain based on two-dimensional gel electrophoresis matrix-assisted laser desorption/ionization MS/MS analysis. Zebrafish. 7(2):169-177
Soza-Ried, C., Hess, I., Netuschil, N., Schorpp, M., and Boehm, T. (2010) Essential role of c-myb in definitive hematopoiesis is evolutionarily conserved. Proceedings of the National Academy of Sciences of the United States of America. 107(40):17304-17308
Fu, Y.F., Du, T.T., Dong, M., Zhu, K.Y., Jing, C.B., Zhang, Y., Wang, L., Fan, H.B., Chen, Y., Jin, Y., Yue, G.P., Chen, S.J., Chen, Z., Huang, Q.H., Jing, Q., Deng, M., and Liu, T.X. (2009) Mir-144 selectively regulates embryonic {alpha}-hemoglobin synthesis during primitive erythropoiesis. Blood. 113(6):1340-1349
Chu, C.Y., Cheng, C.H., Chen, G.D., Chen, Y.C., Hung, C.C., Huang, K.Y., and Huang, C.J. (2007) The zebrafish erythropoietin: Functional identification and biochemical characterization. FEBS letters. 581(22):4265-4271
Roesner, A., Hankeln, T., and Burmester, T. (2006) Hypoxia induces a complex response of globin expression in zebrafish (Danio rerio). The Journal of experimental biology. 209(11):2129-2137
Vihtelic, T.S., Fadool, J.M., Gao, J., Thornton, K.A., Hyde, D.R., and Wistow, G. (2005) Expressed sequence tag analysis of zebrafish eye tissues for NEIBank. Molecular Vision. 11:1083-1100
Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314
Yergeau, D.A., Cornell, C.N., Parker, S.K., Zhou, Y., and Detrich, H.W. 3rd. (2005) bloodthirsty, an RBCC/TRIM gene required for erythropoiesis in zebrafish. Developmental Biology. 283(1):97-112
Vidal, G., Scheffler, B., Michel, A., and D'Surney, S.J. (2004) Genomic and Phylogenic Comparisons of the alpha-Globin and beta-Globin Intergenic Sequences between Zebra Fish (Danio rerio) and Six Closely Related Cyprinindae Species. DNA and cell biology. 23(5):325-334
Chuzhanova, N.A., Krawczak, M., Thomas, N., Nemytikova, L.A., Gusev, V.D., and Cooper, D.N. (2002) The evolution of the vertebrate beta-globin gene promoter. Evolution; international journal of organic evolution. 56(2):224-232
Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
Gates, M.A., Kim, L., Egan, E.S., Cardozo, T., Sirotkin, H.I., Dougan, S.T., Lashkari, D., Abagyan, R., Schier, A.F., and Talbot, W.S. (1999) A genetic linkage map for zebrafish: comparative analysis and localization of genes and expressed sequences. Genome research. 9(4):334-347
Postlethwait, J.H, Yan, Y.-L., Gates, M.A., Horne, S., Amores, A., Brownlie, A., Donovan, A., Egan, E.S., Force, A., Gong, Z., Goutel, C., Fritz, A., Kelsh, R., Knapik, E., Liao, E., Paw, B., Ransom, D., Singer, A., Thomson, M., Abduljabbar, T.S., Yelick, P., Beier, D., Joly, J.-S., Larhammar, D., Rosa, F., Westerfield, M., Zon, L.I., Johnson, S.L., and Talbot, W.S. (1998) Vertebrate genome evolution and the zebrafish gene map. Nature Genetics. 18:345-349
Chan, F.Y., Robinson, J., Brownlie, A., Shivdasani, R.A., Donovan, A., Brugnara, C., Kim, J., Lau, B.C., Witkowska, H.E., and Zon, L.I. (1997) Characterization of adult alpha- and beta-globin genes in the zebrafish. Blood. 89(2):688-700
Additional Citations (17):
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.
ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.
ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.
Thisse, B., Thisse, C. (2004) Fast Release Clones: A High Throughput Expression Analysis. ZFIN Direct Data Submission.
ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.
ZFIN Staff (2004) Temporary Manual Curation. Manually curated data.
Rauch, G.J., Lyons, D.A., Middendorf, I., Friedlander, B., Arana, N., Reyes, T., and Talbot, W.S. (2003) Submission and Curation of Gene Expression Data. ZFIN Direct Data Submission.
ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2002) Scientific Curation. Manually curated data.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
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