ZFIN

ZFIN ID: ZDB-GENE-071119-4

ZFIN ID: ZDB-GENE-071119-4

CITATIONS (59 total)

Gene Name:	growth hormone receptor b
Gene Symbol:	ghrb

Ka, Y., Lee, I., Ji, K. (2024) Thyroid and growth hormone endocrine disruption and mechanisms of homosalate and octisalate using wild-type, thrαa^-/-, and dre-miR-499^-/- zebrafish embryo/larvae. Ecotoxicology and environmental safety. 286:117170117170

Awasthi, N., Ward, A.C., Liongue, C. (2023) Analysis of Potential Non-Canonical or Alternate STAT5 Functions in Immune Development and Growth. Frontiers in bioscience (Landmark edition). 28:187187

Lau, E.S., Zhu, B., Sun, M.A., Ngai, S.M., Ge, W. (2023) Proteomic analysis of zebrafish Folliculogenesis identifies YB-1 (Ybx1/ybx1) as a potential gatekeeping molecule controlling early ovarian Folliculogenesis. Biology of reproduction. 109(4):482-497

Wei, Z., Bagivalu Lakshminarasimha, A., Cone, R., Michel, M. (2023) Loss of Agrp1 in zebrafish: Effects on the growth and reproductive axis. General and comparative endocrinology. 336:114243

Dong, X.R., Wan, S.M., Zhou, J.J., Nie, C.H., Chen, Y.L., Diao, J.H., Gao, Z.X. (2022) Functional Differentiation of BMP7 Genes in Zebrafish: bmp7a for Dorsal-Ventral Pattern and bmp7b for Melanin Synthesis and Eye Development. Frontiers in cell and developmental biology. 10:838721

Zhao, T., Ye, Z., Liu, Y., Lin, H., Li, S., Zhang, Y. (2022) Mutation of spexin2 promotes feeding, somatic growth, adiposity and insulin resistance in zebrafish. American journal of physiology. Regulatory, integrative and comparative physiology. 322(5):R454-R465

Zhou, W., Wang, Y., Wang, J., Peng, C., Wang, Z., Qin, H., Li, G., Li, D. (2022) β-Ionone causes endocrine disruption, hyperpigmentation and hypoactivity in zebrafish early life stages. The Science of the total environment. 834:155433

Hsieh, Y.W., Tsai, Y.W., Lai, H.H., Lai, C.Y., Lin, C.Y., Her, G.M. (2021) Depletion of Alpha-Melanocyte-Stimulating Hormone Induces Insatiable Appetite and Gains in Energy Reserves and Body Weight in Zebrafish. Biomedicines. 9(8):

Lutfi, E., Basili, D., Falcinelli, S., Morillas, L., Carnevali, O., Capilla, E., Navarro, I. (2021) The probiotic Lactobacillus rhamnosus mimics the dark-driven regulation of appetite markers and melatonin receptors' expression in zebrafish (Danio rerio) larvae: Understanding the role of the gut microbiome. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 256:110634

Meirelles, M.G., Nornberg, B.F., da Silveira, T.L.R., Kütter, M.T., Castro, C.G., Ramirez, J.R.B., Pedrosa, V., Romano, L.A., Marins, L.F. (2021) Growth Hormone Overexpression Induces Hyperphagia and Intestinal Morphophysiological Adaptations to Improve Nutrient Uptake in Zebrafish. Frontiers in Physiology. 12:723853

Sua-Cespedes, C.D., David, D.D., Souto-Neto, J.A., Lima, O.G., Moraes, M.N., de Assis, L.V.M., Castrucci, A.M.L. (2021) Low Temperature Effect on the Endocrine and Circadian Systems of Adult Danio rerio. Frontiers in Physiology. 12:707067

Fei, F., Sun, S., Li, Q., Pei, Z., Wang, L., Zhang, R., Luo, F., Yu, M., Wang, X. (2020) Combinatorial normalization of liver-derived cytokine pathways alleviates hepatic tumor-associated cachexia in zebrafish. Cancer research. 81(4):873-884

Knuth, M.M., Mahapatra, D., Jima, D., Wan, D., Hammock, B.D., Law, M., Kullman, S.W. (2020) Vitamin D deficiency serves as a precursor to stunted growth and central adiposity in zebrafish. Scientific Reports. 10:16032

Wang, L., Yan, R., Yang, Q., Li, H., Zhang, J., Shimoda, Y., Kato, K., Yamanaka, K., An, Y. (2020) Role of GH/IGF axis in arsenite-induced developmental toxicity in zebrafish embryos. Ecotoxicology and environmental safety. 201:110820

Zhou, W., Wang, J., Zhang, J., Peng, C., Li, G., Li, D. (2020) Environmentally relevant concentrations of geosmin affect the development, oxidative stress, apoptosis and endocrine disruption of embryo-larval zebrafish. The Science of the total environment. 735:139373

Li, P., Li, Z.H., Zhong, L. (2019) Parental exposure to triphenyltin inhibits growth and disrupts thyroid function in zebrafish larvae. Chemosphere. 240:124936

Ren, X., Wang, W., Zhao, X., Ren, B., Chang, L. (2019) Parental exposure to tris(1,3-dichloro-2-propyl) phosphate results in thyroid endocrine disruption and inhibition of growth in zebrafish offspring. Aquatic toxicology (Amsterdam, Netherlands). 209:132-141

Dang, Y., Wang, F., Liu, C. (2018) Real-time PCR array to study the effects of chemicals on the growth hormone/insulin-like growth factors (GH/IGFs) axis of zebrafish embryos/larvae. Chemosphere. 207:365-376

Huang, P., Xiong, S., Kang, J., Mei, J., Gui, J.F. (2018) Stat5b Regulates Sexually Dimorphic Gene Expression in Zebrafish Liver.. Frontiers in Physiology. 9:676

Huang, Y., Liu, J., Yu, L., Liu, C., Wang, J. (2018) Gonadal impairment and parental transfer of tris (2-butoxyethyl) phosphate in zebrafish after long-term exposure to environmentally relevant concentrations. Chemosphere. 218:449-457

Zeng, X., Sun, H., Huang, Y., Liu, J., Yu, L., Liu, C., Wang, J. (2018) Effects of environmentally relevant concentrations of tris (2-butoxyethyl) phosphate on growth and transcription of genes involved in the GH/IGF and HPT axes in zebrafish (Danio rerio). Chemosphere. 212:376-384

Fei, F., Sun, S.Y., Yao, Y.X., Wang, X. (2017) [Generation and phenotype analysis of zebrafish mutations of obesity-related genes lepr and mc4r]. Sheng li xue bao : [Acta physiologica Sinica]. 69:61-69

Hou, J., Su, Y., Lin, W., Guo, H., Xie, P., Chen, J., Gu, Z., Li, L. (2017) Microcystin-LR retards gonadal maturation through disrupting the growth hormone/insulin-like growth factors system in zebrafish. Ecotoxicology and environmental safety. 139:27-35

Liu, Y., Wu, D., Xu, Q., Yu, L., Liu, C., Wang, J. (2017) Acute exposure to tris (2-butoxyethyl) phosphate (TBOEP) affects growth and development of embryo-larval zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 191:17-24

Schüttler, A., Reiche, K., Altenburger, R., Busch, W. (2017) The transcriptome of the zebrafish embryo after chemical exposure - a meta-analysis. Toxicological sciences : an official journal of the Society of Toxicology. 157(2):291-304

Tian, J., Wang, K., Wang, X., Wen, H., Zhou, H., Liu, C., Mai, K., He, G. (2017) Soybean Saponin Modulates Nutrient Sensing Pathways and Metabolism in Zebrafish. General and comparative endocrinology. 257:246-254

Yu, L., Jia, Y., Su, G., Sun, Y., Letcher, R.J., Giesy, J.P., Yu, H., Han, Z., Liu, C. (2017) Parental transfer of tris(1,3-dichloro-2-propyl) phosphate and transgenerational inhibition of growth of zebrafish exposed to environmentally relevant concentrations. Environmental pollution (Barking, Essex : 1987). 220(Pt A):196-203

Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37

Nornberg, B.F., Almeida, D.V., Figueiredo, M.A., Marins, L.F. (2016) GH indirectly enhances the regeneration of transgenic zebrafish fins through IGF2a and IGF2b. Transgenic Research. 25(5):743-9

Zhou, R., Yu, S.M., Ge, W. (2016) Expression and Functional Characterization of Intrafollicular GH-IGF System in the Zebrafish Ovary. General and comparative endocrinology. 232:32-42

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

Jing, J., Xiong, S., Li, Z., Wu, J., Zhou, L., Gui, J.F., Mei, J. (2015) A feedback regulatory loop involving p53/miR-200 and growth hormone endocrine axis controls embryo size of zebrafish. Scientific Reports. 5:15906

Tian, J., He, G., Mai, K., Liu, C. (2015) Effects of postprandial starvation on mRNA expression of endocrine-, amino acid and peptide transporter-, and metabolic enzyme-related genes in zebrafish (Danio rerio). Fish physiology and biochemistry. 41(3):773-87

Li, M., Gao, Z., Ji, D., Zhang, S. (2014) Functional characterization of GH-like homolog in amphioxus reveals an ancient origin of GH/GH receptor system. Endocrinology. 155:4818-30

Besseau, L., Fuentès, M., Sauzet, S., Beauchaud, M., Chatain, B., Covès, D., Boeuf, G., and Falcón, J. (2013) Somatotropic axis genes are expressed before pituitary onset during zebrafish and sea bass development. General and comparative endocrinology. 194C:133-141

Amaral, I.P., and Johnston, I.A. (2012) Experimental selection for body size at age modifies early-life history traits and muscle gene expression in adult zebrafish. The Journal of experimental biology. 215(22):2895-2904

Tsai, T.C., Lu, J.K., Choo, S.L., Yeh, S.Y., Tang, R.B., Lee, H.Y., and Lu, J.H. (2012) The paracrine effect of exogenous growth hormone alleviates dysmorphogenesis caused by tbx5 deficiency in zebrafish (Danio rerio) embryos. Journal of Biomedical Science. 19(1):63

Chen, M., Huang, X., Yuen, D.S., and Cheng, C.H. (2011) A study on the functional interaction between the GH/PRL family of polypeptides with their receptors in zebrafish: Evidence against GHR1 being the receptor for somatolactin. Molecular and Cellular Endocrinology. 337(1-2):114-21

Di Prinzio, C.M., Botta, P.E., Barriga, E.H., Ríos, E.A., Reyes, A.E., and Arranz, S.E. (2010) Growth hormone receptors in zebrafish (Danio rerio): adult and embryonic expression patterns. Gene expression patterns : GEP. 10(4-5):214-225

Palstra, A.P., Tudorache, C., Rovira, M., Brittijn, S.A., Burgerhout, E., van den Thillart, G.E., Spaink, H.P., and Planas, J.V. (2010) Establishing zebrafish as a novel exercise model: swimming economy, swimming-enhanced growth and muscle growth marker gene expression. PLoS One. 5(12):e14483

Anelli, V., Santoriello, C., Distel, M., Köster, R.W., Ciccarelli, F.D., and Mione, M. (2009) Global repression of cancer gene expression in a zebrafish model of melanoma is linked to epigenetic regulation. Zebrafish. 6(4):417-424

Biga, P.R., and Meyer, J. (2009) Growth hormone differentially regulates growth and growth-related gene expression in closely related fish species. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 154(4):465-473

Braasch, I., Brunet, F., Volff, J.N., and Schartl, M. (2009) Pigmentation pathway evolution after whole-genome duplication in fish. Genome biology and evolution. 1:479-493

Fukamachi, S., and Meyer, A. (2007) Evolution of receptors for growth hormone and somatolactin in fish and land vertebrates: lessons from the lungfish and sturgeon orthologues. Journal of molecular evolution. 65(4):359-372

Liongue, C., and Ward, A.C. (2007) Evolution of Class I cytokine receptors. BMC Evolutionary Biology. 7(1):120

Additional Citations (14):

ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2003) Curation of unpublished nucleotide sequence accession numbers. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.