ZFIN ID: ZDB-GENE-030131-102
CITATIONS (108 total)
Gene Name: cellular communication network factor 2a
Gene Symbol: ccn2a
Chen, M., Liu, Y., Zuo, M., Guo, C., Du, Y., Xu, H., Liu, B., Li, M., Xiao, W., Yu, G. (2024) NEDD8 enhances Hippo signaling by mediating YAP1 neddylation. The Journal of biological chemistry. 300(8):107512
Gupta, S., Hui, S.P. (2024) Epigenetic Cross-Talk Between Sirt1 and Dnmt1 Promotes Axonal Regeneration After Spinal Cord Injury in Zebrafish. Molecular neurobiology. :
Li, S., Shao, R., Li, S., Zhao, J., Deng, Q., Li, P., Wei, Z., Xu, S., Chen, L., Li, B., Zou, W., Zhang, Z. (2024) A monoallelic variant in CCN2 causes an autosomal dominant spondyloepimetaphyseal dysplasia with low bone mass. Bone research. 12:6060
Xiao, W., Hu, C., Ni, Y., Wang, J., Jiao, K., Zhou, M., Li, Z. (2024) 27-Hydroxycholesterol activates the GSK-3β/β-catenin signaling pathway resulting in intestinal fibrosis by inducing oxidative stress: effect of dietary interventions. Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 73(2):289-304
Ye, X., Lin, J., Chen, Q., Lv, J., Liu, C., Wang, Y., Wang, S., Wen, X., Lin, F. (2024) An Efficient Vector-Based CRISPR/Cas9 System in Zebrafish Cell Line. Marine biotechnology (New York, N.Y.). 26(3):588-598
Zebrafish Nomenclature Committee (2024) Nomenclature Data Curation (2024). Nomenclature Committee Submission.
Zhu, M., Li, Y., Shen, Q., Gong, Z., Liu, D. (2024) Sex disparity in zebrafish liver cell proliferation after partial hepatectomy is regulated by sex hormone receptors and the S100A1-YAP signaling cascade. Disease models & mechanisms. 17(10):
Celeghin, R., Risato, G., Beffagna, G., Cason, M., Bueno Marinas, M., Della Barbera, M., Facchinello, N., Giuliodori, A., Brañas Casas, R., Caichiolo, M., Vettori, A., Grisan, E., Rizzo, S., Dalla Valle, L., Argenton, F., Thiene, G., Tiso, N., Pilichou, K., Basso, C. (2023) A novel DSP zebrafish model reveals training- and drug-induced modulation of arrhythmogenic cardiomyopathy phenotypes. Cell death discovery. 9:441441
Chang, S.H., Giong, H.K., Kim, D.Y., Kim, S., Oh, S., Yun, U.J., Lee, J.S., Park, K.W. (2023) Activation of Nrf2 by sulfuretin stimulates chondrocyte differentiation and increases bone lengths in zebrafish. BMB reports. 56:496501496-501
Cigliola, V., Shoffner, A., Lee, N., Ou, J., Gonzalez, T.J., Hoque, J., Becker, C.J., Han, Y., Shen, G., Faw, T.D., Abd-El-Barr, M.M., Varghese, S., Asokan, A., Poss, K.D. (2023) Spinal cord repair is modulated by the neurogenic factor Hb-egf under direction of a regeneration-associated enhancer. Nature communications. 14:48574857
El Maï, M., Bird, M., Allouche, A., Targen, S., Şerifoğlu, N., Lopes-Bastos, B., Guigonis, J.M., Kang, D., Pourcher, T., Yue, J.X., Ferreira, M.G. (2023) Gut-specific telomerase expression counteracts systemic aging in telomerase-deficient zebrafish. Nature aging. 3(5):567-584
Jiao, K., Yang, K., Wang, J., Ni, Y., Hu, C., Liu, J., Zhou, M., Zheng, J., Li, Z. (2023) 27-Hydroxycholesterol induces liver fibrosis via down-regulation of trimethylation of histone H3 at lysine 27 by activating oxidative stress; effect of nutrient interventions. Free radical biology & medicine. 210:462-477
Li, H., Luo, Q., Cai, S., Tie, R., Meng, Y., Shan, W., Xu, Y., Zeng, X., Qian, P., Huang, H. (2023) Glia maturation factor-γ is required for initiation and maintenance of hematopoietic stem and progenitor cells. Stem Cell Research & Therapy. 14:117117
Zhao, Y., Wang, H., He, T., Ma, B., Chen, G., Tzeng, C. (2023) Knockdown of Yap attenuates TAA-induced hepatic fibrosis by interaction with hedgehog signals. Journal of cell communication and signaling. 17(4):1335-1354
Arena, K.A., Zhu, Y., Kucenas, S. (2022) Transforming growth factor-beta signaling modulates perineurial glial bridging following peripheral spinal motor nerve injury in zebrafish. Glia. 70(10):1826-1849
Rayrikar, A.Y., Wagh, G.A., Santra, M., Patra, C. (2022) Ccn2a-FGFR1-SHH signaling is necessary for intervertebral disc homeostasis and regeneration in adult zebrafish. Development (Cambridge, England). 150(1):
Shen, W.Y., Fu, X.H., Cai, J., Li, W.C., Fan, B.Y., Pang, Y.L., Zhao, C.X., Abula, M., Kong, X.H., Yao, X., Feng, S.Q. (2022) Identification of key genes involved in recovery from spinal cord injury in adult zebrafish. Neural regeneration research. 17:1334-1342
Bauer, B., Liedtke, D., Jarzina, S., Stammler, E., Kreisel, K., Lalomia, V., Diefenbacher, M., Klopocki, E., Mally, A. (2021) Exploration of zebrafish larvae as an alternative whole-animal model for nephrotoxicity testing. Toxicology letters. 344:69-81
Camillo, C., Facchinello, N., Villari, G., Mana, G., Gioelli, N., Sandri, C., Astone, M., Tortarolo, D., Clapero, F., Gays, D., Oberkersch, R.E., Arese, M., Tamagnone, L., Valdembri, D., Santoro, M.M., Serini, G. (2021) LPHN2 inhibits vascular permeability by differential control of endothelial cell adhesion. The Journal of cell biology. 220(11):
Campbell, N.R., Rao, A., Hunter, M.V., Sznurkowska, M.K., Briker, L., Zhang, M., Baron, M., Heilmann, S., Deforet, M., Kenny, C., Ferretti, L.P., Huang, T.H., Perlee, S., Garg, M., Nsengimana, J., Saini, M., Montal, E., Tagore, M., Newton-Bishop, J., Middleton, M.R., Corrie, P., Adams, D.J., Rabbie, R., Aceto, N., Levesque, M.P., Cornell, R.A., Yanai, I., Xavier, J.B., White, R.M. (2021) Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation. Developmental Cell. 56(20):2808-2825.e10
Joshi, B., Wagh, G., Kaur, H., Patra, C. (2021) Zebrafish Model to Study Angiotensin II-Mediated Pathophysiology. Biology. 10(11):
Klatt Shaw, D., Saraswathy, V.M., Zhou, L., McAdow, A.R., Burris, B., Butka, E., Morris, S.A., Dietmann, S., Mokalled, M.H. (2021) Localized EMT reprograms glial progenitors to promote spinal cord repair. Developmental Cell. 56(5):613-626.e7
Lai, C.Y., Yeh, K.Y., Lin, C.Y., Hsieh, Y.W., Lai, H.H., Chen, J.R., Hsu, C.C., Her, G.M. (2021) MicroRNA-21 Plays Multiple Oncometabolic Roles in the Process of NAFLD-Related Hepatocellular Carcinoma via PI3K/AKT, TGF-β, and STAT3 Signaling. Cancers. 13(5):
Metikala, S., Casie Chetty, S., Sumanas, S. (2021) Single-cell transcriptome analysis of the zebrafish embryonic trunk. PLoS One. 16:e0254024
Tsai, Y.W., Jeng, K.S., He, M.K., Hsieh, Y.W., Lai, H.H., Lai, C.Y., Huang, C.C., Chang, C.F., Huang, C.T., Her, G.M. (2021) MXD3 Promotes Obesity and the Androgen Receptor Signaling Pathway in Gender-Disparity Hepatocarcinogenesis. Cells. 10(12):
Xia, J., Kang, Z., Xue, Y., Ding, Y., Gao, S., Zhang, Y., Lv, P., Wang, X., Ma, D., Wang, L., Han, J.J., Liu, F. (2021) A single-cell resolution developmental atlas of hematopoietic stem and progenitor cell expansion in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 118(14):
Demirci, Y., Cucun, G., Poyraz, Y.K., Mohammed, S., Heger, G., Papatheodorou, I., Ozhan, G. (2020) Comparative Transcriptome Analysis of the Regenerating Zebrafish Telencephalon Unravels a Resource With Key Pathways During Two Early Stages and Activation of Wnt/β-Catenin Signaling at the Early Wound Healing Stage. Frontiers in cell and developmental biology. 8:584604
Flinn, M.A., Otten, C., Brandt, Z.J., Bostrom, J.R., Kenarsary, A., Wan, T.C., Auchampach, J.A., Abdelilah-Seyfried, S., O'Meara, C.C., Link, B.A. (2020) Llgl1 regulates zebrafish cardiac development by mediating Yap stability in cardiomyocytes. Development (Cambridge, England). 147(16):
Liu, D.J., Zhang, F., Chen, Y., Jin, Y., Zhang, Y.L., Chen, S.B., Xie, Y.Y., Huang, Q.H., Zhao, W.L., Wang, L., Xu, P.F., Chen, Z., Chen, S.J., Li, B., Zhang, A., Sun, X.J. (2020) setd2 knockout zebrafish is viable and fertile: differential and developmental stress-related requirements for Setd2 and histone H3K36 trimethylation in different vertebrate animals. Cell discovery. 6:72
Lundin, V., Sugden, W.W., Theodore, L.N., Sousa, P.M., Han, A., Chou, S., Wrighton, P.J., Cox, A.G., Ingber, D.E., Goessling, W., Daley, G.Q., North, T.E. (2020) YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow. Developmental Cell. 52(4):446-460.e5
Mukherjee, D., Wagh, G., Mokalled, M.H., Kontarakis, Z., Dickson, A.L., Rayrikar, A., Günther, S., Poss, K.D., Stainier, D.Y.R., Patra, C. (2020) Ccn2a/Ctgfa is an injury-induced matricellular factor that promotes cardiac regeneration in zebrafish. Development (Cambridge, England). 148(2):
Tsata, V., Kroehne, V., Wehner, D., Rost, F., Lange, C., Hoppe, C., Kurth, T., Reinhardt, S., Petzold, A., Dahl, A., Loeffler, M., Reimer, M.M., Brand, M. (2020) Reactive oligodendrocyte progenitor cells (re-)myelinate the regenerating zebrafish spinal cord. Development (Cambridge, England). 147(24):
Wu, S.Y., Yang, W.Y., Cheng, C.C., Hsiao, M.C., Tsai, S.L., Lin, H.K., Lin, K.H., Yuh, C.H. (2020) Low Molecular Weight Fucoidan Prevents Radiation-Induced Fibrosis and Secondary Tumors in a Zebrafish Model. Cancers. 12(6):
Wu, S.Y., Yang, W.Y., Cheng, C.C., Lin, K.H., Sampurna, B.P., Chan, S.M., Yuh, C.H. (2020) Low molecular weight fucoidan inhibits hepatocarcinogenesis and nonalcoholic fatty liver disease in zebrafish via ASGR/STAT3/HNF4A signaling. Clinical and translational medicine. 10:e252
Moro, A., Driscoll, T.P., Boraas, L.C., Armero, W., Kasper, D.M., Baeyens, N., Jouy, C., Mallikarjun, V., Swift, J., Ahn, S.J., Lee, D., Zhang, J., Gu, M., Gerstein, M., Schwartz, M., Nicoli, S. (2019) MicroRNA-dependent regulation of biomechanical genes establishes tissue stiffness homeostasis. Nature cell biology. 21(3):348-358
Pan, W.Q., Wang, J.P., Tu, Z.H., Gan, T., Hu, J., Wei, J., Leng, X.J., Li, X.Q. (2019) Cloning, molecular characterization, and tissue differential expression of connective tissue growth factor (ctgf) of grass carp. Fish physiology and biochemistry. 45(4):1431-1443
Su, Z.L., Su, C.W., Huang, Y.L., Yang, W.Y., Sampurna, B.P., Ouchi, T., Lee, K.L., Wu, C.S., Wang, H.D., Yuh, C.H. (2019) A Novel AURKA Mutant-Induced Early-Onset Severe Hepatocarcinogenesis Greater than Wild-Type via Activating Different Pathways in Zebrafish. Cancers. 11(7)
Xue, Y., Liu, D., Cui, G., Ding, Y., Ai, D., Gao, S., Zhang, Y., Suo, S., Wang, X., Lv, P., Zhou, C., Li, Y., Chen, X., Peng, G., Jing, N., Han, J.J., Liu, F. (2019) A 3D Atlas of Hematopoietic Stem and Progenitor Cell Expansion by Multi-dimensional RNA-Seq Analysis. Cell Reports. 27:1567-1578.e5
Barta, C.L., Liu, H., Chen, L., Giffen, K.P., Li, Y., Kramer, K.L., Beisel, K.W., He, D.Z. (2018) RNA-seq transcriptomic analysis of adult zebrafish inner ear hair cells. Scientific data. 5:180005
Chou, Y.T., Chen, L.Y., Tsai, S.L., Tu, H.C., Lu, J.W., Ciou, S.C., Wang, H.D., Yuh, C.H. (2018) Ribose-5-Phosphate Isomerase A Overexpression Promotes Liver Cancer Development in Transgenic Zebrafish via Activation of ERK and β-catenin Pathways. Carcinogenesis. 40(3):461-473
Cox, A.G., Tsomides, A., Yimlamai, D., Hwang, K.L., Miesfeld, J., Galli, G.G., Fowl, B.H., Fort, M., Ma, K.Y., Sullivan, M.R., Hosios, A.M., Snay, E., Yuan, M., Brown, K.K., Lien, E.C., Chhangawala, S., Steinhauser, M.L., Asara, J.M., Houvras, Y., Link, B., Vander Heiden, M.G., Camargo, F.D., Goessling, W. (2018) Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth. The EMBO journal. 37(22):
Flinn, M.A., Jeffery, B.E., O'Meara, C.C., Link, B.A. (2018) Yap is Required for Scar Formation but not Myocyte Proliferation During Heart Regeneration in Zebrafish. Cardiovascular research. 115(3):570-577
Giuliodori, A., Beffagna, G., Marchetto, G., Fornetto, C., Vanzi, F., Toppo, S., Facchinello, N., Santimaria, M., Vettori, A., Rizzo, S., Della Barbera, M., Pilichou, K., Argenton, F., Thiene, G., Tiso, N., Basso, C. (2018) Loss of cardiac Wnt/β-catenin signalling in Desmoplakin-deficient AC8 zebrafish models is rescuable by genetic and pharmacological intervention. Cardiovascular research. 114(8):1082-1097
Maheras, A.L., Dix, B., Carmo, O.M.S., Young, A.E., Gill, V.N., Sun, J.L., Booker, A.R., Thomason, H.A., Ibrahim, A.E., Stanislaw, L., Dallego, J.C., Ngo, C.N., Chen, A., Fortini, B.K., Spence, R.D. (2018) Genetic Pathways of Neuroregeneration in a Novel Mild Traumatic Brain Injury Model in Adult Zebrafish. eNeuro. 5(1)
Oh, H., Kim, C.Y., Ryu, B., Kim, U., Kim, J., Lee, J.M., Lee, B.H., Moon, J., Jung, C.R., Park, J.H. (2018) Respiratory Toxicity of Polyhexamethylene Guanidine Phosphate Exposure in Zebrafish. Zebrafish. 15(5):460-472
Subramanian, A., Kanzaki, L.F., Galloway, J.L., Schilling, T.F. (2018) Mechanical force regulates tendon extracellular matrix organization and tenocyte morphogenesis through TGFbeta signaling. eLIFE. 7:
Vera-Chang, M.N., St-Jacques, A.D., Gagné, R., Martyniuk, C.J., Yauk, C.L., Moon, T.W., Trudeau, V.L. (2018) Transgenerational hypocortisolism and behavioral disruption are induced by the antidepressant fluoxetine in male zebrafish Danio rerio. Proceedings of the National Academy of Sciences of the United States of America. 115(52):E12435-E12442
Xu, D., Lv, J., He, L., Fu, L., Hu, R., Cao, Y., Mei, C. (2018) Scribble influences cyst formation in autosomal-dominant polycystic kidney disease by regulating Hippo signaling pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 32(8):4394-4407
Askary, A., Xu, P., Barske, L., Bay, M., Bump, P., Balczerski, B., Bonaguidi, M.A., Crump, J.G. (2017) Genome-wide analysis of facial skeletal regionalization in zebrafish. Development (Cambridge, England). 144(16):2994-3005
Chiba, A., Watanabe-Takano, H., Terai, K., Fukui, H., Miyazaki, T., Uemura, M., Hashimoto, H., Hibi, M., Fukuhara, S., Mochizuki, N. (2017) Osteocrin, a peptide secreted from the heart and other tissues, contributes to cranial osteogenesis and chondrogenesis in zebrafish. Development (Cambridge, England). 144(2):334-344
Jagadeeshan, S., Sagayaraj, R.V., Paneerselvan, N., Ghouse, S.S., Malathi, R. (2017) Toxicity and anti-angiogenicity evaluation of Pak1 inhibitor IPA-3 using zebrafish embryo model. Cell biology and toxicology. 33(1):41-56
Kimelman, D., Smith, N.L., Lai, J.K.H., Stainier, D.Y. (2017) Regulation of posterior body and epidermal morphogenesis in Zebrafish by localized Yap1 and Wwtr1. eLIFE. 6
Mayrhofer, M., Gourain, V., Reischl, M., Affaticati, P., Jenett, A., Joly, J.S., Benelli, M., Demichelis, F., Poliani, P.L., Sieger, D., Mione, M. (2017) A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK/PI3K induced malignant growth. Disease models & mechanisms. 10(1):15-28
Nagasawa-Masuda, A., Terai, K. (2017) Yap/Taz transcriptional activity is essential for vascular regression via Ctgf expression and actin polymerization. PLoS One. 12:e0174633
Pfefferli, C., Jaźwińska, A. (2017) The careg element reveals a common regulation of regeneration in the zebrafish myocardium and fin. Nature communications. 8:15151
Xia, Z., Wei, J., Li, Y., Wang, J., Li, W., Wang, K., Hong, X., Zhao, L., Chen, C., Min, J., Wang, F. (2017) Zebrafish slc30a10 deficiency revealed a novel compensatory mechanism of Atp2c1 in maintaining manganese homeostasis. PLoS Genetics. 13:e1006892
Yu, C., Yao, X., Zhao, L., Wang, P., Zhang, Q., Zhao, C., Yao, S., Wei, Y. (2017) Wolf-Hirschhorn Syndrome Candidate 1 (whsc1) Functions as a Tumor Suppressor by Governing Cell Differentiation. Neoplasia (New York, N.Y.). 19:606-616
Zhang, W., Liu, B., Feng, Y., Liu, J., Ma, Z., Zheng, J., Xia, Q., Ni, Y., Li, F., Lin, R. (2017) Anti-angiogenic Activity of Water Extract from Euphorbia pekinensis Rupr. Journal of ethnopharmacology. 206:337-346
Burger, A., Lindsay, H., Felker, A., Hess, C., Anders, C., Chiavacci, E., Zaugg, J., Weber, L.M., Catena, R., Jinek, M., Robinson, M.D., Mosimann, C. (2016) Maximizing mutagenesis with solubilized CRISPR-Cas9 ribonucleoprotein complexes. Development (Cambridge, England). 143(11):2025-37
Cox, A.G., Hwang, K.L., Brown, K.K., Evason, K.J., Beltz, S., Tsomides, A., O'Connor, K., Galli, G.G., Yimlamai, D., Chhangawala, S., Yuan, M., Lien, E.C., Wucherpfennig, J., Nissim, S., Minami, A., Cohen, D.E., Camargo, F.D., Asara, J.M., Houvras, Y., Stainier, D.Y., Goessling, W. (2016) Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth. Nature cell biology. 18(8):886-96
Grampa, V., Delous, M., Zaidan, M., Odye, G., Thomas, S., Elkhartoufi, N., Filhol, E., Niel, O., Silbermann, F., Lebreton, C., Collardeau-Frachon, S., Rouvet, I., Alessandri, J.L., Devisme, L., Dieux-Coeslier, A., Cordier, M.P., Capri, Y., Khung-Savatovsky, S., Sigaudy, S., Salomon, R., Antignac, C., Gubler, M.C., Benmerah, A., Terzi, F., Attié-Bitach, T., Jeanpierre, C., Saunier, S. (2016) Novel NEK8 Mutations Cause Severe Syndromic Renal Cystic Dysplasia through YAP Dysregulation. PLoS Genetics. 12:e1005894
Mokalled, M.H., Patra, C., Dickson, A.L., Endo, T., Stainier, D.Y., Poss, K.D. (2016) Injury-induced ctgfa directs glial bridging and spinal cord regeneration in zebrafish. Science (New York, N.Y.). 354:630-634
Paul, S., Schindler, S., Giovannone, D., de Millo Terrazzani, A., Mariani, F.V., Crump, J.G. (2016) Ihha induces hybrid cartilage-bone cells during zebrafish jawbone regeneration. Development (Cambridge, England). 143(12):2066-76
Progatzky, F., Cook, H.T., Lamb, J.R., Bugeon, L., Dallman, M.J. (2016) Mucosal inflammation at the respiratory interface: a zebrafish model. American journal of physiology. Lung cellular and molecular physiology. 310(6):L551-61
Sasagawa, S., Nishimura, Y., Okabe, S., Murakami, S., Ashikawa, Y., Yuge, M., Kawaguchi, K., Kawase, R., Okamoto, R., Ito, M., Tanaka, T. (2016) Downregulation of GSTK1 Is a Common Mechanism Underlying Hypertrophic Cardiomyopathy. Frontiers in pharmacology. 7:162
Thyme, S.B., Schier, A.F. (2016) Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development. Cell Reports. 15(4):707-714
Mateus, R., Lourenço, R., Fang, Y., Brito, G., Farinho, A., Valério, F., Jacinto, A. (2015) Control of tissue growth by Yap relies on cell density and F-actin in zebrafish fin regeneration. Development (Cambridge, England). 142(16):2752-63
Merkes, C., Turkalo, T.K., Wilder, N., Park, H., Wenger, L.W., Lewin, S.J., Azuma, M. (2015) Ewing Sarcoma Ewsa Protein Regulates Chondrogenesis of Meckel's Cartilage through Modulation of Sox9 in Zebrafish. PLoS One. 10:e0116627
Miesfeld, J.B., Gestri, G., Clark, B.S., Flinn, M.A., Poole, R.J., Bader, J.R., Besharse, J.C., Wilson, S.W., Link, B.A. (2015) Yap and Taz regulate retinal pigment epithelial cell fate. Development (Cambridge, England). 142(17):3021-32
Fukui, H., Terai, K., Nakajima, H., Chiba, A., Fukuhara, S., Mochizuki, N. (2014) S1P-Yap1 Signaling Regulates Endoderm Formation Required for Cardiac Precursor Cell Migration in Zebrafish. Developmental Cell. 31:128-136
Gagnon, J.A., Valen, E., Thyme, S.B., Huang, P., Ahkmetova, L., Pauli, A., Montague, T.G., Zimmerman, S., Richter, C., Schier, A.F. (2014) Efficient Mutagenesis by Cas9 Protein-Mediated Oligonucleotide Insertion and Large-Scale Assessment of Single-Guide RNAs. PLoS One. 9:e98186
Liu, C.L., Kwok, H.F., Cheng, L., Ko, C.H., Wong, C.W., Ho, T.W., Leung, P.C., Fung, K.P., and Lau, C.B. (2014) Molecular mechanisms of angiogenesis effect of active sub-fraction from root of Rehmannia glutinosa by zebrafish sprout angiogenesis-guided fractionation. Journal of ethnopharmacology. 151(1):565-575
Lu, J.W., Liao, C.Y., Yang, W.Y., Lin, Y.M., Jin, S.L., Wang, H.D., and Yuh, C.H. (2014) Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway. PLoS One. 9(1):e85318
Lu, J.W., Yang, W.Y., Lin, Y.M., Jin, S.L., and Yuh, C.H. (2013) Hepatitis B virus X antigen and aflatoxin B1 synergistically cause hepatitis, steatosis and liver hyperplasia in transgenic zebrafish. Acta histochemica. 115(7):728-39
Lu, J.W., Yang, W.Y., Tsai, S.M., Lin, Y.M., Chang, P.H., Chen, J.R., Wang, H.D., Wu, J.L., Jin, S.L., and Yuh, C.H. (2013) Liver-Specific Expressions of HBx and src in the p53 Mutant Trigger Hepatocarcinogenesis in Zebrafish. PLoS One. 8(10):e76951
Liu, W., Chen, J.R., Hsu, C.H., Li, Y.H., Chen, Y.M., Lin, C.Y., Huang, S.J., Chang, Z.K., Chen, Y.C., Lin, C.H., Gong, H.Y., Lin, C.C., Kawakami, K., and Wu, J.L. (2012) A zebrafish model of intrahepatic cholangiocarcinoma by dual expression of hepatitis B virus X and hepatitis C virus core protein in liver. Hepatology (Baltimore, Md.). 56(6):2268-2276
Sucularli, C., Senturk, S., Ozturk, M., and Konu, O. (2011) Dose- and time-dependent expression patterns of zebrafish orthologs of selected E2F target genes in response to serum starvation/replenishment. Molecular biology reports. 38(6):4111-23
Zheng, W., Wang, Z., Collins, J.E., Andrews, R.M., Stemple, D., and Gong, Z. (2011) Comparative transcriptome analyses indicate molecular homology of zebrafish swimbladder and Mammalian lung. PLoS One. 6(8):e24019
Fernando, C.A., Conrad, P.A., Bartels, C.F., Marques, T., To, M., Balow, S.A., Nakamura, Y., and Warman, M.L. (2010) Temporal and spatial expression of CCN genes in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 239(6):1755-1767
Rastegar, S., Hess, I., Dickmeis, T., Nicod, J.C., Ertzer, R., Hadzhiev, Y., Thies, W.G., Scherer, G., and Strähle, U. (2008) The words of the regulatory code are arranged in a variable manner in highly conserved enhancers. Developmental Biology. 318(2):366-377
Rekha, R.D., Amali, A.A., Her, G.M., Yeh, Y.H., Gong, H.Y., Hu, S.Y., Lin, G.H., and Wu, J.L. (2008) Thioacetamide accelerates steatohepatitis, cirrhosis and HCC by expressing HCV core protein in transgenic zebrafish Danio rerio. Toxicology. 243(1-2):11-22
Chiou, M.J., Chao, T.T., Wu, J.L., Kuo, C.M., and Chen, J.Y. (2006) The physiological role of CTGF/CCN2 in zebrafish notochond development and biological analysis of the proximal promoter region. Biochemical and Biophysical Research Communications. 349(2):750-758
Norton, W.H., Mangoli, M., Lele, Z., Pogoda, H.M., Diamond, B., Mercurio, S., Russell, C., Teraoka, H., Stickney, H.L., Rauch, G.J., Heisenberg, C.P., Houart, C., Schilling, T.F., Frohnhoefer, H.G., Rastegar, S., Neumann, C.J., Gardiner, R.M., Strähle, U., Geisler, R., Rees, M., Talbot, W.S., and Wilson, S.W. (2005) Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphe neurones and cranial motoneurones. Development (Cambridge, England). 132(4):645-658
Dickmeis, T., Plessy, C., Rastegar, S., Aanstad, P., Herwig, R., Chalmel, F., Fischer, N., and Strähle, U. (2004) Expression profiling and comparative genomics identify a conserved regulatory region controlling midline expression in the zebrafish embryo. Genome research. 14(2):228-238
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Additional Citations (21):
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.
ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
Varshney, G.K., Zhang, S., Burgess, S.M., ZFIN Staff (2015) Automated Data Load From CRISPRz. ZFIN Direct Data Submission.
Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.
Thisse, C., and Thisse, B. (2005) High Throughput Expression Analysis of ZF-Models Consortium Clones. ZFIN Direct Data Submission.
ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.
Rauch, G.J., Lyons, D.A., Middendorf, I., Friedlander, B., Arana, N., Reyes, T., and Talbot, W.S. (2003) Submission and Curation of Gene Expression Data. ZFIN Direct Data Submission.
Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.
ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.
ZFIN Staff (2003) Curation of orthology data. Manually curated data.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2002) Scientific Curation. Manually curated data.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Curation of EMBL records. Automated Data Submission.
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