Gene

ccn2a

ID

ZDB-GENE-030131-102

Name

cellular communication network factor 2a

Symbol

ccn2a Nomenclature History

Previous Names

ctgf
ctgfa
hm:zeh1559
si:dkey-266k12.4
wu:fl25c03 (1)
zCTGF-c20 (1)
zgc:136644

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to have heparin binding activity and integrin binding activity. Involved in several processes, including endoderm development; notochord development; and regeneration. Predicted to localize to extracellular matrix. Is expressed in several structures, including digestive system; fin; head; mesoderm; and spinal cord. Orthologous to human CCN2 (cellular communication network factor 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

44 figures from 28 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu936 (12 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ccn2a Human Ortholog

No data available

Associated With ccn2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000867	Insulin-like growth factor-binding protein, IGFBP
Domain	IPR001007	VWFC domain
Domain	IPR006207	Cystine knot, C-terminal
Domain	IPR006208	Glycoprotein hormone subunit beta
Domain	IPR043973	CCN, TSP1 domain
Family	IPR012395	IGFBP-related, CNN
Family	IPR050941	Cellular Communication Network Factor
Homologous_superfamily	IPR009030	Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily	IPR036383	Thrombospondin type-1 (TSP1) repeat superfamily
Repeat	IPR000884	Thrombospondin type-1 (TSP1) repeat