ZFIN

ZFIN ID: ZDB-GENE-021115-2

ZFIN ID: ZDB-GENE-021115-2

CITATIONS (92 total)

Gene Name:	transient receptor potential cation channel, subfamily M, member 7
Gene Symbol:	trpm7

Bowley, G., Irving, S., Hoefer, I., Wilkinson, R., Pasterkamp, G., Darwish, H.M.S., White, S., Francis, S.E., Chico, T., Noel, E., Serbanovic-Canic, J., Evans, P.C. (2024) Zebrafish model for functional screening of flow-responsive genes controlling endothelial cell proliferation. Scientific Reports. 14:3013030130

Watai, K., Sadamitsu, K., Wada, S., Kashima, M., Hirata, H. (2024) Zebrafish trpm7 mutants show reduced motility in free movement. Development, growth & differentiation. 66(6):349-356

Belcher, B., Vestal, J., Lane, S., Kell, M., Smith, L., Camarata, T. (2023) The zebrafish paralog six2b is required for early proximal pronephros morphogenesis. Scientific Reports. 13:1969919699

Wesselman, H.M., Flores-Mireles, A.L., Bauer, A., Pei, L., Wingert, R.A. (2023) Esrrγa regulates nephron and ciliary development by controlling prostaglandin synthesis. Development (Cambridge, England). 150(10):

Wesselman, H.M., Gatz, A.E., Pfaff, M.R., Arceri, L., Wingert, R.A. (2023) Estrogen Signaling Influences Nephron Segmentation of the Zebrafish Embryonic Kidney. Cells. 12(4):

Weaver, N.E., Healy, A., Wingert, R.A. (2022) gldc Is Essential for Renal Progenitor Patterning during Kidney Development. Biomedicines. 10(12):

Chambers, B.E., Clark, E.G., Gatz, A.E., Wingert, R.A. (2020) Kctd15 regulates nephron segment development by repressing Tfap2a activity. Development (Cambridge, England). 147(23):

Chambers, J.M., Addiego, A., Flores-Mireles, A.L., Wingert, R.A. (2020) Ppargc1a Controls Ciliated Cell Development by Regulating Prostaglandin Biosynthesis. Cell Reports. 33:108370

Gross-Thebing, S., Truszkowski, L., Tenbrinck, D., Sánchez-Iranzo, H., Camelo, C., Westerich, K.J., Singh, A., Maier, P., Prengel, J., Lange, P., Hüwel, J., Gaede, F., Sasse, R., Vos, B.E., Betz, T., Matis, M., Prevedel, R., Luschnig, S., Diz-Muñoz, A., Burger, M., Raz, E. (2020) Using migrating cells as probes to illuminate features in live embryonic tissues. Science advances. 6(49):

Xie, H., Kang, Y., Wang, S., Zheng, P., Chen, Z., Roy, S., Zhao, C. (2020) E2f5 is a versatile transcriptional activator required for spermatogenesis and multiciliated cell differentiation in zebrafish. PLoS Genetics. 16:e1008655

You, M.S., Yang, W.B., Cheng, C.H., Yu, S., Chang, H.C., Yu, H.S. (2020) Red LED light treatment promotes cognitive learning through up-regulation of trpm4 in zebrafish. Journal of photochemistry and photobiology. B, Biology. 213:112073

Chambers, B.E., Gerlach, G.F., Clark, E.G., Chen, K.H., Levesque, A.E., Leshchiner, I., Goessling, W., Wingert, R.A. (2019) Tfap2a is a novel gatekeeper of nephron differentiation during kidney development. Development (Cambridge, England). 146(13):

Marra, A.N., Adeeb, B.D., Chambers, B.E., Drummond, B.E., Ulrich, M., Addiego, A., Springer, M., Poureetezadi, S.J., Chambers, J.M., Ronshaugen, M., Wingert, R.A. (2019) Prostaglandin signaling regulates renal multiciliated cell specification and maturation. Proceedings of the National Academy of Sciences of the United States of America. 116(17):8409-8418

Marra, A.N., Cheng, C.N., Adeeb, B., Addiego, A., Wesselman, H.M., Chambers, B.E., Chambers, J.M., Wingert, R.A. (2019) Iroquois transcription factor irx2a is required for multiciliated and transporter cell fate decisions during zebrafish pronephros development. Scientific Reports. 9:6454

Barrodia, P., Patra, C., Swain, R.K. (2018) EF-hand domain containing 2 (Efhc2) is crucial for distal segmentation of pronephros in zebrafish. Cell & Bioscience. 8:53

Chambers, J.M., Poureetezadi, S.J., Addiego, A., Lahne, M., Wingert, R.A. (2018) ppargc1a controls nephron segmentation during zebrafish embryonic kidney ontogeny. eLIFE. 7:

Drummond, B.E., Li, Y., Marra, A.N., Cheng, C.N., Wingert, R.A. (2017) The tbx2a/b transcription factors direct pronephros segmentation and corpuscle of Stannius formation in zebrafish. Developmental Biology. 421(1):52-66

Horstick, E.J., Bayleyen, Y., Sinclair, J.L., Burgess, H.A. (2017) Search strategy is regulated by somatostatin signaling and deep brain photoreceptors in zebrafish. BMC Biology. 15:4

Bhandari, S., Lee, J.N., Kim, Y.I., Nam, I.K., Kim, S.J., Kim, S.J., Kwak, S., Oh, G.S., Kim, H.J., Yoo, H.J., So, H.S., Choe, S.K., Park, R. (2016) The fatty acid chain elongase, Elovl1, is required for kidney and swim bladder development during zebrafish embryogenesis. Organogenesis. 12(2):78-93

Jansen, C., Sahni, J., Suzuki, S., Horgen, F.D., Penner, R., Fleig, A. (2016) The coiled-coil domain of zebrafish TRPM7 regulates Mg·nucleotide sensitivity. Scientific Reports. 6:33459

Ott, E., Wendik, B., Srivastava, M., Pacho, F., Töchterle, S., Salvenmoser, W., Meyer, D. (2016) Pronephric tubule morphogenesis in zebrafish depends on Mnx mediated repression of irx1b within the intermediate mesoderm. Developmental Biology. 411(1):101-14

Poureetezadi, S.J., Cheng, C.N., Chambers, J.M., Drummond, B.E., Wingert, R.A. (2016) Prostaglandin signaling regulates nephron segment patterning of renal progenitors during zebrafish kidney development. eLIFE. 5

Cheng, C.N., Wingert, R.A. (2015) Nephron proximal tubule patterning and corpuscles of Stannius formation are regulated by the sim1a transcription factor and retinoic acid in zebrafish. Developmental Biology. 399(1):100-16

Diep, C.Q., Peng, Z., Ukah, T.K., Kelly, P.M., Daigle, R.V., Davidson, A.J. (2015) Development of the zebrafish mesonephros. Genesis (New York, N.Y. : 2000). 53(3-4):257-69

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

He, L., Xu, W., Jing, Y., Wu, M., Song, S., Cao, Y., Mei, C. (2015) Yes-Associated Protein (Yap) Is Necessary for Ciliogenesis and Morphogenesis during Pronephros Development in Zebrafish (Danio Rerio). International journal of biological sciences. 11:935-47

Sugano, Y., Lindenmeyer, M.T., Auberger, I., Ziegler, U., Segerer, S., Cohen, C.D., Neuhauss, S.C., Loffing, J. (2015) The Rho-GTPase binding protein IQGAP2 is required for the glomerular filtration barrier. Kidney International. 88(5):1047-56

Decker, A.R., McNeill, M.S., Lambert, A.M., Overton, J.D., Chen, Y.C., Lorca, R.A., Johnson, N.A., Brockerhoff, S.E., Mohapatra, D.P., Macarthur, H., Panula, P., Masino, M.A., Runnels, L.W., and Cornell, R.A. (2014) Abnormal differentiation of dopaminergic neurons in zebrafish trpm7 mutant larvae impairs development of the motor pattern. Developmental Biology. 386(2):428-39

Gerlach, G.F., Wingert, R.A. (2014) Zebrafish pronephros tubulogenesis and epithelial identity maintenance are reliant on the polarity proteins Prkc iota and zeta. Developmental Biology. 396(2):183-200

Li, Y., Cheng, C.N., Verdun, V.A., and Wingert, R.A. (2014) Zebrafish nephrogenesis is regulated by interactions between retinoic acid, mecom, and Notch signaling. Developmental Biology. 386(1):111-122

Marra, A.N., Wingert, R.A. (2014) Roles of Iroquois Transcription Factors in Kidney Development. Cell & developmental biology. 3(1):1000131

Wang, Y., Sun, Z.H., Zhou, L., Li, Z., Gui, J.F. (2014) Grouper tshbeta Promoter-Driven Transgenic Zebrafish Marks Proximal Kidney Tubule Development. PLoS One. 9:e97806

Graham, D.M., Huang, L., Robinson, K.R., and Messerli, M.A. (2013) Epidermal keratinocyte polarity and motility require Ca²⁺ influx through TRPV1. Journal of Cell Science. 126(Pt 20):4602-13

Kastenhuber, E., Gesemann, M., Mickoleit, M., and Neuhauss, S.C. (2013) Phylogenetic analysis and expression of zebrafish transient receptor potential melastatin family genes. Developmental Dynamics : an official publication of the American Association of Anatomists. 242(11):1236-49

Lam, P.Y., Kamei, C.N., Mangos, S., Mudumana, S., Liu, Y., and Drummond, I.A. (2013) odd-skipped related 2 is required for fin chondrogenesis in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 242(11):1284-92

Naylor, R.W., Przepiorski, A., Ren, Q., Yu, J., and Davidson, A.J. (2013) HNF1beta Is Essential for Nephron Segmentation during Nephrogenesis. Journal of the American Society of Nephrology : JASN. 24(1):77-87

Sah, R., Mesirca, P., Van den Boogert, M., Rosen, J., Mably, J., Mangoni, M.E., and Clapham, D.E. (2013) Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity. Proceedings of the National Academy of Sciences of the United States of America. 110(3):E3037-E3046

Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735

Wang, L., Fu, C., Fan, H., Du, T., Dong, M., Chen, Y., Jin, Y., Zhou, Y., Deng, M., Gu, A., Jing, Q., Liu, T., and Zhou, Y. (2013) miR-34b regulates multiciliogenesis during organ formation in zebrafish. Development (Cambridge, England). 140(13):2755-2764

Low, S.E., Amburgey, K., Horstick, E., Linsley, J., Sprague, S.M., Cui, W.W., Zhou, W., Hirata, H., Saint-Amant, L., Hume, R.I., and Kuwada, J.Y. (2011) TRPM7 Is Required within Zebrafish Sensory Neurons for the Activation of Touch-Evoked Escape Behaviors. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(32):11633-11644

Sander, J.D., Dahlborg, E.J., Goodwin, M.J., Cade, L., Zhang, F., Cifuentes, D., Curtin, S.J., Blackburn, J.S., Thibodeau-Beganny, S., Qi, Y., Pierick, C.J., Hoffman, E., Maeder, M.L., Khayter, C., Reyon, D., Dobbs, D., Langenau, D.M., Stupar, R.M., Giraldez, A.J., Voytas, D.F., Peterson, R.T., Yeh, J.R., Joung, J.K. (2011) Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA). Nature Methods. 8:67-9

Wingert, R.A., and Davidson, A.J. (2011) Zebrafish nephrogenesis involves dynamic spatiotemporal expression changes in renal progenitors and essential signals from retinoic acid and irx3b. Developmental Dynamics : an official publication of the American Association of Anatomists. 240(8):2011-2027

Yee, N.S., Zhou, W., and Liang, I.C. (2011) Transient receptor potential ion channel Trpm7 regulates exocrine pancreatic epithelial proliferation by Mg2+-sensitive Socs3a signaling in development and cancer. Disease models & mechanisms. 4(2):240-254

Elizondo, M.R., Budi, E.H., and Parichy, D.M. (2010) trpm7 Regulation of in Vivo Cation Homeostasis and Kidney Function Involves Stanniocalcin 1 and fgf23. Endocrinology. 151(12):5700-5709

Tan, S.H., Chung, H.H., and Shu-Chien, A.C. (2010) Distinct developmental expression of two elongase family members in zebrafish. Biochemical and Biophysical Research Communications. 393(3):397-403

Vasilyev, A., Liu, Y., Mudumana, S., Mangos, S., Lam, P.Y., Majumdar, A., Zhao, J., Poon, K.L., Kondrychyn, I., Korzh, V., and Drummond, I.A. (2009) Collective Cell Migration Drives Morphogenesis of the Kidney Nephron. PLoS Biology. 7(1):e9

Mudumana, S.P., Hentschel, D., Liu, Y., Vasilyev, A., and Drummond, I.A. (2008) odd skipped related1 reveals a novel role for endoderm in regulating kidney versus vascular cell fate. Development (Cambridge, England). 135(20):3355-3367

Hsiao, C.D., You, M.S., Guh, Y.J., Ma, M., Jiang, Y.J., and Hwang, P.P. (2007) A Positive Regulatory Loop between foxi3a and foxi3b Is Essential for Specification and Differentiation of Zebrafish Epidermal Ionocytes. PLoS One. 2(1):e302

Liu, Y., Pathak, N., Kramer-Zucker, A., and Drummond, I.A. (2007) Notch signaling controls the differentiation of transporting epithelia and multiciliated cells in the zebrafish pronephros. Development (Cambridge, England). 134(6):1111-1122

McNeill, M.S., Paulsen, J., Bonde, G., Burnight, E., Hsu, M.Y., and Cornell, R.A. (2007) Cell Death of Melanophores in Zebrafish trpm7 Mutant Embryos Depends on Melanin Synthesis. The Journal of investigative dermatology. 127(8):2020-30

Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433

Wingert, R.A., Selleck, R., Yu, J., Song, H.D., Chen, Z., Song, A., Zhou, Y., Thisse, B., Thisse, C., McMahon, A.P., and Davidson, A.J. (2007) The cdx Genes and Retinoic Acid Control the Positioning and Segmentation of the Zebrafish Pronephros. PLoS Genetics. 3(10):1922-1938

Elizondo, M.R., Arduini, B.L., Paulsen, J., MacDonald, E.L., Sabel, J.L., Henion, P.D., Cornell, R.A., Parichy, D.M. (2005) Defective Skeletogenesis with Kidney Stone Formation in Dwarf Zebrafish Mutant for trpm7. Current biology : CB. 15(7):667-671

Arduini, B.L., and Henion, P.D. (2004) Melanophore sublineage-specific requirement for zebrafish touchtone during neural crest development. Mechanisms of Development. 121(11):1353-1364

Cornell, R.A., Yemm, E., Bonde, G., Li, W., d'Alencon, C., Wegman, L., Eisen, J., and Zahs, A. (2004) Touchtone promotes survival of embryonic melanophores in zebrafish. Mechanisms of Development. 121(11):1365-1376

Rawls, J.F., Frieda, M.R., McAdow, A.R., Gross, J.P., Clayton, C.M., Heyen, C.K., and Johnson, S.L. (2003) Coupled mutagenesis screens and genetic mapping in zebrafish. Genetics. 163(3):997-1009

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Kelsh, R.N., Schmid, B., and Eisen, J.S. (2000) Genetic analysis of melanophore development in zebrafish embryos. Developmental Biology. 225(2):277-293

Ribera, A.B. and Nüsslein-Volhard, C. (1998) Zebrafish touch-insensitive mutants reveal an essential role for the developmental regulation of sodium current. The Journal of neuroscience : the official journal of the Society for Neuroscience. 18:9181-9191

Granato, M., van Eeden, F.J., Schach, U., Trowe, T., Brand, M., Furutani-Seiki, M., Haffter, P., Hammerschmidt, M., Heisenberg, C.P., Jiang, Y.J., Kane, D.A., Kelsh, R.N., Mullins, M.C., Odenthal, J., and Nüsslein-Volhard, C. (1996) Genes controlling and mediating locomotion behavior of the zebrafish embryo and larva. Development (Cambridge, England). 123:399-413

Haffter, P., Granato, M., Brand, M., Mullins, M.C., Hammerschmidt, M., Kane, D.A., Odenthal, J., van Eeden, F.J., Jiang, Y.J., Heisenberg, C.P., Kelsh, R.N., Furutani-Seiki, M., Vogelsang, E., Beuchle, D., Schach, U., Fabian, C., and Nüsslein-Volhard, C. (1996) The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio. Development (Cambridge, England). 123:1-36

Kelsh, R.N., Brand, M., Jiang, Y.J., Heisenberg, C.P., Lin, S., Haffter, P., Odenthal, J., Mullins, M.C., van Eeden, F.J., Furutani-Seiki, M., Granato, M., Hammerschmidt, M., Kane, D.A., Warga, R.M., Beuchle, D., Vogelsang, L., and Nüsslein-Volhard, C. (1996) Zebrafish pigmentation mutations and the processes of neural crest development. Development (Cambridge, England). 123:369-389

Additional Citations (30):

ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

Geisler, R. (2013) Importation of Tübingen internal allele names. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

ZIRC and ZFIN staff (2013) Mutant and Transgenic Line Submissions 2013. ZFIN Direct Data Submission.

Burgess, S., and Lin, S. (2012) Viral Insertion Mutants Overwrite Data. ZFIN Direct Data Submission.

Burgess, S., and Lin, S. (2011) Viral Insertion Mutants. ZFIN Direct Data Submission.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZIRC and ZFIN Staff (2008) Mutant and Transgenic Line Submissions 2008. ZFIN Direct Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZIRC and ZFIN Staff (2007) Mutant and Transgenic Line Submissions. ZFIN Direct Data Submission.

Phenotype Annotation (1994-2006) (2006) Mutant Data Curated from Older Literature. ZFIN Historical Data.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

ZFIN Staff (2003) Submission and Curation of Mutant and Transgenic Lines. ZFIN Direct Data Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2003) Gene Ontology Annotation Through Association of Enzyme Commission numbers with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.

Thisse, B., Pflumio, S., Fürthauer, M., Loppin, B., Heyer, V., Degrave, A., Woehl, R., Lux, A., Steffan, T., Charbonnier, X.Q. and Thisse, C. (2001) Expression of the zebrafish genome during embryogenesis (NIH R01 RR15402). ZFIN Direct Data Submission.