ZFIN

ZFIN ID: ZDB-GENE-010716-2

ZFIN ID: ZDB-GENE-010716-2

CITATIONS (45 total)

Gene Name:	iroquois homeobox 5a
Gene Symbol:	irx5a

Liu, Y., Kassack, M.E., McFaul, M.E., Christensen, L.N., Siebert, S., Wyatt, S.R., Kamei, C.N., Horst, S., Arroyo, N., Drummond, I.A., Juliano, C.E., Draper, B.W. (2022) Single-cell transcriptome reveals insights into the development and function of the zebrafish ovary. eLIFE. 11:

Thiruppathy, M., Fabian, P., Gillis, J.A., Crump, J.G. (2022) Gill developmental program in the teleost mandibular arch. eLIFE. 11

Farmer, D.T., Patel, P., Choi, R., Liu, C.Y., Crump, J.G. (2021) Comprehensive series of Irx cluster mutants reveals diverse roles in facial cartilage development. Development (Cambridge, England). 148(16)

Kohl, S., Llavona, P., Sauer, A., Reuter, P., Weisschuh, N., Kempf, M., Dehmelt, F.A., Arrenberg, A.B., Sliesoraityte, I., Zrenner, E., van Schooneveld, M.J., Rudolph, G., Kühlewein, L., Wissinger, B. (2021) A duplication on chromosome 16q12 affecting the IRXB gene cluster is associated with autosomal dominant cone dystrophy with early tritanopic color vision defect. Human molecular genetics. 30(13):1218-1229

Mitchell, J.M., Sucharov, J., Pulvino, A.T., Brooks, E.P., Gillen, A.E., Nichols, J.T. (2021) The alx3 gene shapes the zebrafish neurocranium by regulating frontonasal neural crest cell differentiation timing. Development (Cambridge, England). 148(7):

Askary, A., Xu, P., Barske, L., Bay, M., Bump, P., Balczerski, B., Bonaguidi, M.A., Crump, J.G. (2017) Genome-wide analysis of facial skeletal regionalization in zebrafish. Development (Cambridge, England). 144(16):2994-3005

Mullally, M., Albrecht, C., Horton, M., Laboissonniere, L.A., Goetz, J.J., Chowdhury, R., Manning, A., Wester, A.K., Bose, Q., Trimarchi, J.M. (2016) Expression Profiling of Developing Zebrafish Retinal Cells. Zebrafish. 13(4):272-80

Wu, M., Wu, D., Wang, C., Guo, Z., Li, B., Zuo, Z. (2016) Hexabromocyclododecane exposure induces cardiac hypertrophy and arrhythmia by inhibiting miR-1 expression via up-regulation of the homeobox gene Nkx2.5. Journal of hazardous materials. 302:304-313

Askary, A., Mork, L., Paul, S., He, X., Izuhara, A.K., Gopalakrishnan, S., Ichida, J.K., McMahon, A.P., Dabizljevic, S., Dale, R., Mariani, F.V., Crump, J.G. (2015) Iroquois Proteins Promote Skeletal Joint Formation by Maintaining Chondrocytes in an Immature State. Developmental Cell. 35:358-65

Diotel, N., Viales, R.R., Armant, O., März, M., Ferg, M., Rastegar, S., Strähle, U. (2015) Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. The Journal of comparative neurology. 523(8):1202-21

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

Orosz, F. (2015) On the tubulin polymerization promoting proteins of zebrafish. Biochemical and Biophysical Research Communications. 457(3):267-72

Wolf, A., and Ryu, S. (2013) Specification of posterior hypothalamic neurons requires coordinated activities of Fezf2, Otp, Sim1a and Foxb1.2. Development (Cambridge, England). 140(8):1762-1773

Choe, S.K., Zhang, X., Hirsch, N., Straubhaar, J., and Sagerström, C.G. (2011) A screen for hoxb1-regulated genes identifies ppp1r14al as a regulator of the rhombomere 4 Fgf-signaling center. Developmental Biology. 358(2):356-67

Tena, J.J., Alonso, M.E., de la Calle-Mustienes, E., Splinter, E., de Laat, W., Manzanares, M., and Gómez-Skarmeta, J.L. (2011) An evolutionarily conserved three-dimensional structure in the vertebrate Irx clusters facilitates enhancer sharing and coregulation. Nature communications. 2:310

Choy, S.W., Cheng, C.W., Lee, S.T., Li, V.W., Hui, M.N., Hui, C.C., Liu, D., and Cheng, S.H. (2010) A cascade of irx1a and irx2a controls shh expression during retinogenesis. Developmental Dynamics : an official publication of the American Association of Anatomists. 239(12):3204-3214

McDonald, L.A., Gerrelli, D., Fok, Y., Hurst, L.D., and Tickle, C. (2010) Comparison of Iroquois gene expression in limbs/fins of vertebrate embryos. Journal of anatomy. 216(6):683-691

Cheng, C.W., Yan, C.H., Choy, S.W., Hui, M.N., Hui, C.C., and Cheng, S.H. (2007) Zebrafish homologue irx1a is required for the differentiation of serotonergic neurons. Developmental Dynamics : an official publication of the American Association of Anatomists. 236(9):2661-2667

de la Calle-Mustienes, E., Feijoo, C.G., Manzanares, M., Tena, J.J., Rodriguez-Seguel, E., Leticia, A., Allende, M.L., and Gomez-Skarmeta, J.L. (2005) A functional survey of the enhancer activity of conserved non-coding sequences from vertebrate Iroquois cluster gene deserts. Genome research. 15(8):1061-1072

Lecaudey, V., Anselme, I., Dildrop, R., Ruther, U., and Schneider-Maunoury, S. (2005) Expression of the zebrafish Iroquois genes during early nervous system formation and patterning. The Journal of comparative neurology. 492(3):289-302

Dildrop, R., and Ruther, U. (2004) Organization of Iroquois genes in fish. Development genes and evolution. 214(6):267-276

Feijoo, C.G., Manzanares, M., De La Calle-Mustienes, E., Gómez-Skarmeta, J.L., and Allende, M.L. (2004) The Irx gene family in zebrafish: genomic structure, evolution and initial characterization of irx5b. Development genes and evolution. 214(6):277-284

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Wang, X., Emelyanov, A., Sleptsova-Friedrich, I., Korzh, V., and Gong, Z. (2001) Expression of two novel zebrafish iroquois homologues (ziro1 and ziro5) during early development of axial structures and central nervous system. Mechanisms of Development. 105(1-2):191-195

Additional Citations (21):

ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

UniProt curators (2015) Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features.. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

GOA curators, UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. Manually curated data.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

Thisse, B., Thisse, C. (2004) Fast Release Clones: A High Throughput Expression Analysis. ZFIN Direct Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

ZFIN Staff (2004) Temporary Manual Curation. Manually curated data.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of EMBL records. Automated Data Submission.