Gene
irx5a
- ID
- ZDB-GENE-010716-2
- Name
- iroquois homeobox 5a
- Symbol
- irx5a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have sequence-specific DNA binding activity. Involved in embryonic skeletal joint development and regulation of chondrocyte differentiation. Predicted to localize to nucleus. Is expressed in several structures, including brain; head; hindbrain neural plate; mesoderm; and midbrain neural keel. Orthologous to human IRX5 (iroquois homeobox 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 22 figures from 14 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92554 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Hamamy syndrome | 611174 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Iroquois-class homeodomain protein | KN homeodomain |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q1S3
|
242 | |||||
|
UniProtKB:Q1LXU5
|
446 |
Interactions and Pathways
No data available
Plasmids
No data available