Publication	Data		Fish	Anatomy
Al-Dahmani et al., 2022	Fig. 2		li1Tg + MO1-pdx1	pronephric glomerulus increased length, abnormal pronephric tubule decreased length, abnormal
Wiggenhauser et al., 2022	Fig. 1		pdx1uh10/uh10; li1Tg ,   pdx1uh10/+; li1Tg	pronephric glomerulus increased length, abnormal pronephric tubule decreased length, abnormal pronephros decreased functionality, abnormal
	Fig. 2		pdx1uh10/uh10; li1Tg ,   pdx1uh10/+; li1Tg	glomerular basement membrane increased thickness, abnormal renal glomerulus cell increased amount, abnormal renal glomerulus hypertrophic, abnormal renal glomerulus increased area, abnormal
	Fig. 4		li1Tg + MO1-pdx1 ,   pdx1uh10/+; li1Tg	kidney hexose decreased amount, abnormal kidney phosphoethanolamine increased amount, abnormal pronephric glomerulus increased length, abnormal pronephric tubule decreased length, abnormal
Schmitner et al., 2021	Fig. S1		pdx1sa280/sa280	blood increased concentration blood glucose, abnormal
	Fig. S2		pdx1sa280/sa280	retinal outer nuclear layer cell decreased amount, abnormal retinal outer nuclear layer cell population proliferation increased process quality, abnormal
	Figure 1		pdx1sa280/sa280	photoreceptor cell photoreceptor outer segment truncated, abnormal retinal outer nuclear layer decreased thickness, abnormal
	Figure 4		pdx1sa280/sa280	ciliary marginal zone cell population proliferation decreased process quality, abnormal
	Figure 7		pdx1sa280/sa280; nl1Tg	retinal inner nuclear layer EGFP expression increased distribution, abnormal
Titialii-Torres et al., 2021	Fig. 1		pdx1sa280/sa280 ,   pdx1sa280/sa280; fl1Tg	long double cone cell decreased amount, abnormal long double cone cell zpr-1 labeling decreased distribution, abnormal retinal cone cell cell body decreased thickness, abnormal retinal cone cell cone photoreceptor outer segment decreased length, abnormal retinal rod cell decreased amount, abnormal retinal rod cell EGFP expression decreased distribution, abnormal retinal rod cell rod photoreceptor outer segment decreased length, abnormal retinal rod cell rod photoreceptor outer segment decreased thickness, abnormal short double cone cell decreased amount, abnormal short double cone cell zpr-1 labeling decreased distribution, abnormal
	Fig. 3		pdx1sa280/sa280	long double cone cell cone photoreceptor outer segment truncated, abnormal long double cone cell cone photoreceptor outer segment zpr-3 labeling spatial pattern, abnormal retinal rod cell rod photoreceptor outer segment truncated, abnormal retinal rod cell rod photoreceptor outer segment zpr-3 labeling spatial pattern, abnormal short double cone cell cone photoreceptor outer segment truncated, abnormal short double cone cell cone photoreceptor outer segment zpr-3 labeling spatial pattern, abnormal visual behavior decreased process quality, abnormal
	Fig. 4		pdx1sa280/sa280; mi2001Tg ,   pdx1sa280/+; mi2001Tg	Muller cell cell body increased size, abnormal Muller cell GFP expression spatial pattern, abnormal Muller cell morphology, abnormal
	Fig. 6		pdx1sa280/sa280	retinal ganglion cell layer cell population proliferation increased process quality, abnormal retinal outer nuclear layer cell population proliferation decreased process quality, abnormal
	Fig. S1		pdx1sa280/sa280	whole organism glucose increased amount, abnormal
	text only		pdx1sa280/sa280	whole organism glucose increased amount, abnormal
Ali et al., 2020	Fig. 1		pdx1sa280/sa280; y1Tg/+	retina blood vessel constricted, abnormal retina blood vessel decreased diameter, abnormal retina blood vessel increased branchiness, abnormal retina blood vessel kinked, abnormal retina sprouting angiogenesis increased occurrence, abnormal
	Fig. 2		pdx1sa280/sa280; y1Tg/+	retina artery constricted, abnormal retina artery decreased diameter, abnormal retina capillary increased branchiness, abnormal retina sprouting angiogenesis increased occurrence, abnormal
	Fig. 3		pdx1sa280/sa280; y1Tg/+	artery retina ab1-tagln labeling absent, abnormal retina mural cell decreased amount, abnormal retina vasculature ab1-glul labeling absent, abnormal retina vasculature ab2-tjp1 labeling absent, abnormal
	Fig. 4		pdx1sa280/sa280; y1Tg/+	blood vessel endothelium cell-cell junction loose, abnormal blood vessel tight junction loose, abnormal capillary basement membrane disorganized, abnormal capillary vesicle increased amount, abnormal mural cell cell-cell junction loose, abnormal retina blood vessel increased permeability, abnormal
	Fig. 5		pdx1sa280/sa280; y1Tg/+	blue sensitive photoreceptor cell decreased amount, abnormal green sensitive photoreceptor cell decreased amount, abnormal Muller cell ab1-glul labeling increased distribution, abnormal Muller cell hypertrophic, abnormal red sensitive photoreceptor cell decreased amount, abnormal retina cone photoreceptor outer segment decreased length, abnormal retinal inner nuclear layer nucleus increased amount, abnormal retinal outer nuclear layer chromatin condensed, abnormal retinal outer nuclear layer Muller cell increased amount, abnormal retinal outer nuclear layer nucleus decreased amount, abnormal retinal rod cell decreased amount, abnormal
	Fig. 6		pdx1sa280/sa280; y1Tg/+	green sensitive photoreceptor cell zpr-1 labeling decreased distribution, abnormal green sensitive photoreceptor cell zpr-1 labeling spatial pattern, abnormal photoreceptor activity decreased process quality, abnormal red sensitive photoreceptor cell zpr-1 labeling decreased distribution, abnormal red sensitive photoreceptor cell zpr-1 labeling spatial pattern, abnormal retinal outer nuclear layer retinal cone cell decreased amount, abnormal retinal outer nuclear layer retinal cone cell decreased length, abnormal retinal outer nuclear layer retinal cone cell disorganized, abnormal
Lou et al., 2020	Fig. 3		y1Tg + MO1-pdx1	intersegmental vessel increased branchiness, abnormal intersegmental vessel morphology, abnormal
	Fig. 4		y1Tg + MO1-pdx1	ocular blood vessel sprouting angiogenesis increased process quality, abnormal
	Fig. 5		WT + MO1-pdx1 ,   ml2Tg + MO1-pdx1	pancreas decreased size, abnormal whole organism ins expression decreased amount, abnormal
	Fig. 7		WT + MO1-pdx1	whole organism ADP decreased amount, abnormal whole organism glucose increased amount, abnormal
	Fig. S6		WT + MO1-pdx1	whole organism aldh1a3 expression increased amount, abnormal whole organism aldh1l2 expression increased amount, abnormal whole organism aldh3a1 expression increased amount, abnormal whole organism aldh3b1 expression increased amount, abnormal whole organism aldh7a1 expression decreased amount, abnormal
Wiggenhauser et al., 2020	Fig. 1		pdx1uh10/uh10	whole organism pdx1 expression absent, abnormal
	Fig. 2		pdx1uh10/+; ml2Tg ,   pdx1uh10/uh10; ml2Tg	endocrine pancreas development decreased process quality, abnormal glucose homeostasis decreased process quality, abnormal primary islet decreased area, abnormal whole organism glucose increased amount, abnormal
	Fig. 3		pdx1uh10/uh10; y1Tg ,   ubs1Tg + MO1-pdx1	hyaloid vessel increased branchiness, abnormal hyaloid vessel increased diameter, abnormal hyaloid vessel sprouting angiogenesis increased process quality, abnormal inner optic circle increased diameter, abnormal ocular blood vessel has extra parts of type hyaloid vessel nucleus, abnormal
	Fig. 4		pdx1uh10/uh10; y1Tg	glucose homeostasis decreased process quality, abnormal ocular blood vessel increased branchiness, abnormal ocular blood vessel sprouting angiogenesis increased process quality, abnormal
	Fig. 5		pdx1uh10/+; y1Tg	glucose homeostasis decreased process quality, abnormal ocular blood vessel increased branchiness, abnormal ocular blood vessel sprouting angiogenesis increased process quality, abnormal
	Fig. 6		pdx1uh10/uh10; y1Tg	hyaloid vessel increased branchiness, abnormal hyaloid vessel sprouting angiogenesis increased process quality, abnormal
	Fig. 7		pdx1uh10/uh10; y1Tg	hyaloid vessel increased diameter, abnormal inner optic circle increased diameter, abnormal
	Fig. 8		pdx1uh10/uh10	whole organism glucose increased amount, abnormal whole organism glutamic acid increased amount, abnormal whole organism ornithine decreased amount, abnormal whole organism proline increased amount, abnormal whole organism spermidine decreased amount, abnormal whole organism taurine increased amount, abnormal whole organism tyrosine decreased amount, abnormal
Schmöhl et al., 2019	Fig. 10		y1Tg + MO1-pdx1	pronephric tubule decreased length, abnormal renal glomerulus increased length, abnormal vasculature morphology, abnormal
	Fig. 9		WT + MO1-pdx1	whole organism glucose increased amount, abnormal
She et al., 2017	Fig. 7		li1Tg + MO1-pdx1	pronephric glomerulus increased size, abnormal pronephric tubule decreased length, abnormal pronephros renal filtration decreased occurrence, abnormal
O'Hare et al., 2016	Fig. 2		jh1Tg; jh2Tg + MO1-pdx1	pancreatic B cell decreased amount, abnormal
	Fig. S10		nl1Tg + MO1-pdx1	endocrine pancreas decreased size, abnormal endocrine pancreas development disrupted, abnormal endocrine pancreas EGFP expression decreased distribution, abnormal enteroendocrine cell differentiation disrupted, abnormal
	Fig. S15		jh1Tg; jh2Tg + MO1-pdx1	glucose homeostasis disrupted, abnormal
	Fig. S8		jh1Tg; jh2Tg + CRISPR1-pdx1	pancreatic B cell decreased amount, abnormal pancreatic B cell decreased area, abnormal
Sharma et al., 2016	Fig. 3		li1Tg + MO1-pdx1	pronephric glomerulus increased width, abnormal pronephric tubule decreased length, abnormal pronephros morphogenesis decreased process quality, abnormal
	Fig. 5		li1Tg + MO1-pdx1	pronephric podocyte podocyte development decreased process quality, abnormal pronephric podocyte podocyte foot dystrophic, abnormal pronephric podocyte podocyte foot malformed, abnormal
	Fig. 6		li1Tg + MO1-pdx1	pronephric glomerulus increased width, abnormal pronephric tubule decreased length, abnormal pronephros morphogenesis decreased process quality, abnormal pronephros renal filtration decreased occurrence, abnormal
Jörgens et al., 2015	Fig. 2		y1Tg + MO1-pdx1 + MO4-tp53	blood vessel increased branchiness, abnormal blood vessel morphology, abnormal intersegmental vessel morphology, abnormal intersegmental vessel structure, abnormal
Kimmel et al., 2015	Fig. 1		pdx1sa280/sa280	whole organism decreased size, abnormal whole organism decreased weight, abnormal
	Fig. 2		pdx1sa280/sa280	exocrine pancreas disorganized, abnormal exocrine pancreas polarity, abnormal pancreatic acinar cell absent, abnormal
	Fig. 3		pdx1sa280/sa280; nl1Tg	endocrine pancreas decreased size, abnormal pancreatic B cell decreased amount, abnormal secondary islet absent, abnormal secondary islet decreased amount, abnormal secondary islet EGFP expression absent, abnormal
	Fig. 4		pdx1sa280/sa280	endocrine pancreas ab1-ins labeling decreased amount, abnormal whole organism ins expression decreased amount, abnormal
Jurczyk et al., 2011	Fig. 6		zf5Tg + MO1-pdx1	endocrine pancreas hypoplastic, abnormal glucose metabolic process disrupted, abnormal
Kimmel et al., 2011	Fig. 1		WT + MO1-pdx1	endocrine pancreas development disrupted, abnormal pancreatic B cell decreased amount, abnormal posterior pancreatic bud decreased size, abnormal
	Fig. 3		m1018Tg; nl1Tg + MO1-pdx1	endocrine pancreas decreased size, abnormal endocrine pancreas development disrupted, abnormal endocrine pancreas has fewer parts of type endodermal cell, abnormal pancreatic B cell decreased amount, abnormal type B pancreatic cell differentiation disrupted, abnormal type B pancreatic cell proliferation disrupted, abnormal
Yee et al., 2001	Fig. 1		WT + MO1-pdx1	acinar cell decreased amount, abnormal determination of digestive tract left/right asymmetry process quality, abnormal determination of liver left/right asymmetry process quality, abnormal determination of pancreatic left/right asymmetry process quality, abnormal digestive system positional polarity, abnormal endocrine pancreas decreased functionality, abnormal endocrine pancreas decreased size, abnormal exocrine pancreas hypoplastic, abnormal