Gene
ctbp2a
- ID
- ZDB-GENE-010130-2
- Name
- C-terminal binding protein 2a
- Symbol
- ctbp2a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor binding activity; transcription coregulator activity; and transcription coregulator binding activity. Acts upstream of or within several processes, including nervous system development; regulation of gliogenesis; and regulation of melanocyte differentiation. Predicted to be active in nucleus. Is expressed in nervous system; neural plate; otic vesicle; pectoral fin; and pharyngeal arch. Orthologous to human CTBP2 (C-terminal binding protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 21 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77268 (10 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR029753 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site |
| Domain | IPR006139 | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain |
| Domain | IPR006140 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain |
| Family | IPR043322 | C-terminal binding protein |
| Family | IPR051638 | C-terminal-binding dehydrogenase |
1 - 5 of 6 Show all
Domain Details Per Protein
| Protein | Additional Resources | Length | C-terminal-binding dehydrogenase | C-terminal binding protein | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site | NAD(P)-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q5BU19 | InterPro | 1147 | ||||||
| UniProtKB:Q9DEG6 | InterPro | 444 | ||||||
| UniProtKB:A0AB32T3T5 | InterPro | 435 | ||||||
| UniProtKB:A0AB32T658 | InterPro | 1240 | ||||||
| UniProtKB:A0AB32T7H4 | InterPro | 1200 |
1 - 5 of 9 Show all
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ctbp2a-201
(1)
|
Ensembl | 3,746 nt | ||
| mRNA |
ctbp2a-202
(1)
|
Ensembl | 3,447 nt | ||
| mRNA |
ctbp2a-203
(1)
|
Ensembl | 3,035 nt | ||
| mRNA |
ctbp2a-204
(1)
|
Ensembl | 3,471 nt | ||
| mRNA |
ctbp2a-205
(1)
|
Ensembl | 825 nt |
1 - 5 of 16 Show all
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| AB2-ctbp2a | Chicken |
|
1 | ||||
| Ab1-ctbp2a | polyclonal | Rabbit |
|
10 |
1 - 2 of 2
Plasmids
No data available