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Gene

ctbp2a

ID
ZDB-GENE-010130-2
Name
C-terminal binding protein 2a
Symbol
ctbp2a Nomenclature History
Previous Names
  • CtBP2 (1)
  • ctbp2
  • fe05b01
  • riba
  • ribeye a (1)
  • wu:fb96g03 (1)
  • wu:fe05b01 (1)
  • wu:fk19e02
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to enable NAD binding activity; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; and transcription corepressor activity. Acts upstream of or within camera-type eye development; nervous system development; and regulation of melanocyte differentiation. Predicted to be located in nucleus. Is expressed in nervous system; neural plate; otic vesicle; pectoral fin; and pharyngeal arch. Orthologous to human CTBP2 (C-terminal binding protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
20 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ctbp2a Human Ortholog
No data available
Associated With ctbp2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site
Domain IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
Domain IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
Family IPR043322 C-terminal binding protein
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length C-terminal binding protein D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site NAD(P)-binding domain superfamily
UniProtKB:Q5BU18 670
UniProtKB:A0A2R8QBA1 1200
UniProtKB:F1QMW3 1148
UniProtKB:Q9DEG6 444
UniProtKB:F8W377 165
UniProtKB:A0A0R4IFH8 1196
UniProtKB:Q7SZN5 405
UniProtKB:F8W4E9 1156
UniProtKB:Q6NZ25 404
UniProtKB:Q5BU19 1147
UniProtKB:A9UL56 710
UniProtKB:F8W3U1 670
UniProtKB:Q7ZVY6 404
UniProtKB:F8W3Q3 150
UniProtKB:F8W509 251
UniProtKB:F8W438 189
UniProtKB:F8W571 313
UniProtKB:F1RA12 710
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
AB2-ctbp2a Chicken
1
Ab1-ctbp2a polyclonal Rabbit
  • IHC
9
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations