Gene
ctbp2a
- ID
- ZDB-GENE-010130-2
- Name
- C-terminal binding protein 2a
- Symbol
- ctbp2a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable several functions, including transcription coactivator activity; transcription coregulator binding activity; and transcription corepressor activity. Acts upstream of or within several processes, including nervous system development; regulation of gliogenesis; and regulation of melanocyte differentiation. Predicted to be active in nucleus. Is expressed in nervous system; neural plate; otic vesicle; pectoral fin; and pharyngeal arch. Orthologous to human CTBP2 (C-terminal binding protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 21 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77268 (10 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR029753 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site |
Domain | IPR006139 | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain |
Domain | IPR006140 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain |
Family | IPR043322 | C-terminal binding protein |
Homologous_superfamily | IPR036291 | NAD(P)-binding domain superfamily |
Domain Details Per Protein
Protein | Length | C-terminal binding protein | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site | NAD(P)-binding domain superfamily |
---|---|---|---|---|---|---|
UniProtKB:F8W571
|
313 | |||||
UniProtKB:A9UL56
|
710 | |||||
UniProtKB:Q6NZ25
|
404 | |||||
UniProtKB:F8W4E9
|
1156 | |||||
UniProtKB:F8W438
|
189 | |||||
UniProtKB:F8W377
|
165 | |||||
UniProtKB:F8W3Q3
|
150 | |||||
UniProtKB:Q5BU18
|
670 | |||||
UniProtKB:Q7SZN5
|
405 | |||||
UniProtKB:F1RA12
|
710 | |||||
UniProtKB:Q5BU19
|
1147 | |||||
UniProtKB:F1QMW3
|
1148 | |||||
UniProtKB:A0A2R8QBA1
|
1200 | |||||
UniProtKB:A0A0R4IFH8
|
1196 | |||||
UniProtKB:Q7ZVY6
|
404 | |||||
UniProtKB:Q9DEG6
|
444 | |||||
UniProtKB:F8W3U1
|
670 | |||||
UniProtKB:F8W509
|
251 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
ctbp2a-201
(1)
|
3746 nt | |
mRNA |
ctbp2a-203
(1)
|
3035 nt | |
mRNA |
ctbp2a-204
(1)
|
3471 nt | |
mRNA |
ctbp2a-205
(1)
|
825 nt | |
mRNA |
ctbp2a-206
(1)
|
2013 nt | |
mRNA |
ctbp2a-207
(1)
|
2877 nt | |
mRNA |
ctbp2a-208
(1)
|
2605 nt | |
mRNA |
ctbp2a-209
(1)
|
1197 nt | |
mRNA |
ctbp2a-210
(1)
|
937 nt | |
mRNA |
ctbp2a-211
(1)
|
765 nt | |
mRNA |
ctbp2a-212
(1)
|
2375 nt | |
mRNA |
ctbp2a-213
(1)
|
592 nt |
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
AB2-ctbp2a | Chicken |
|
1 | ||||
Ab1-ctbp2a | polyclonal | Rabbit |
|
10 |
Plasmids
No data available