|
Shox and shox2 knockdown affect expression levels of the natriuretic peptide genes nppa, nppb and nppc in a tissue-specific manner. Relative expression levels upon shox(A), shox2(B) and shox/shox2(C) knockdown in fin (n=3), heart (n=4-5), head (n=4) and whole embryo (n=6). Statistical significance was determined by multiple unpaired t-tests adjusted by the two-stage step-up method of Benjamini, Krieger, and Yekutieli (adjusted values of P are indicated as black asterisks, nominal significant values of P are indicated as colored asterisks). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001). MO = morpholino, hpf = hours post fertilization, n = number of independent experiments.
|
