Gene
nppa
- ID
- ZDB-GENE-030131-95
- Name
- natriuretic peptide A
- Symbol
- nppa Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have hormone activity and hormone receptor binding activity. Involved in atrioventricular canal development; cardiac jelly development; and cardiac muscle cell proliferation. Predicted to localize to cytoplasm; extracellular space; and nucleus. Human ortholog(s) of this gene implicated in artery disease (multiple); congestive heart failure; familial atrial fibrillation; and peritonitis. Is expressed in heart rudiment; pericardial region; and skeletal muscle cell. Orthologous to human NPPA (natriuretic peptide A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 133 figures from 97 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu811 (11 images)
- eu878 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| atrial standstill 2 | Alliance | Atrial standstill 2 | 615745 |
| familial atrial fibrillation | Alliance | Atrial fibrillation, familial, 6 | 612201 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Natriuretic peptide | Natriuretic peptide, conserved site |
|---|---|---|---|
|
UniProtKB:F1QVW0
|
139 |
Interactions and Pathways
No data available
Plasmids
No data available