FIGURE

Figure 1

ID

ZDB-FIG-260505-76

Publication

Hoffmann et al., 2026 - Linking shox/shox2 deficiency with fgfr3 gain-of-function and natriuretic peptides

Other Figures

All Figure Page

Back to All Figure Page

Figure 1

Shox knockdown affects shox2 activity and vice versa: Tissue-specific nCounter analysis of shox and shox2 expression in zebrafish embryos 55 hpf upon shox and shox2 single knockdown (A, B) and shox/shox2 double knockdown (C) in fin (n=3), heart (n=4-5), head (n=4) and whole embryo (n=6). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. MO = morpholino, hpf = hours post fertilization, n = number of independent experiments.

Expression Data

Genes:	shox shox2
Fish:	f1Tg (AB/TU) f1Tg + MO3-shox (AB/TU) f1Tg + MO3-shox2 (AB/TU) f1Tg + MO3-shox + MO3-shox2 (AB/TU)
Knockdown Reagents:	MO3-shox MO3-shox2
Anatomical Terms:	head heart pectoral fin whole organism
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	f1Tg + MO3-shox (AB/TU) f1Tg + MO3-shox2 (AB/TU) f1Tg + MO3-shox + MO3-shox2 (AB/TU)
Knockdown Reagents:	MO3-shox MO3-shox2
Observed In:	head heart pectoral fin whole organism
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Endocrinol (Lausanne)