FIGURE

Fig. 5

ID

ZDB-FIG-260108-63

Publication

Ahn et al., 2025 - The role of AP2M1 in oncofetal characteristics: integrative in silico, in vitro, and in vivo analyses using zebrafish models

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Fig. 5

AP2M1 is associated with Wnt signaling pathway. A Relative mRNA expression of AXIN2 (Wnt), HES1 (Notch), and GLI1 (Hedgehog) following AP2M1 knockdown in HepG2 cells. Data were quantified and expressed as the mean ± SEM of 3 independent experiments. **p < 0.01, ***p < 0.001 vs. value in the negative control. B Relative mRNA expression of AXIN2 (Wnt), HES1 (Notch), and GLI1 (Hedgehog) following AP2M1 knockdown in Hep3B cells. Data were quantified and expressed as the mean ± SEM of 3 independent experiments. **p < 0.01, ***p < 0.001 vs. value in the negative control. C Relative mRNA expression of axin2 (Wnt), her6 (Notch), and gli1 (Hedgehog) in 48hpf zebrafish embryos was detected by RT-PCR. Data were quantified and expressed as the mean ± SEM of 3 independent experiments. **p < 0.01 and ***p < 0.001 vs. value in the negative control

Expression Data

Genes:	axin2 gli1 her6
Fish:	AB AB + MO2-ap2m1a
Knockdown Reagent:	MO2-ap2m1a
Anatomical Term:	whole organism
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO2-ap2m1a
Knockdown Reagent:	MO2-ap2m1a
Observed In:	whole organism
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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