Gene
gli1
- ID
- ZDB-GENE-030321-1
- Name
- GLI family zinc finger 1
- Symbol
- gli1 Nomenclature History
- Previous Names
-
- detour
- dtr
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in several processes, including muscle cell fate specification; nervous system development; and positive regulation of smoothened signaling pathway. Localizes to Hedgehog signaling complex. Is expressed in several structures, including central nervous system; head; neural plate; neural tube; and paraxial mesoderm. Orthologous to human GLI1 (GLI family zinc finger 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 56 figures from 44 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu934 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- 30 figures from 14 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| preaxial polydactyly I | Alliance | Polydactyly, preaxial I | 174400 |
| Polydactyly, postaxial, type A8 | 618123 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | C2H2-type zinc-finger protein GLI-like | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|
|
UniProtKB:Q800Z9
|
1404 | |||
|
UniProtKB:F1QAC4
|
1404 |
- Genome Browsers
Interactions and Pathways
Plasmids
No data available