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Ahn et al., 2025 - The role of AP2M1 in oncofetal characteristics: integrative in silico, in vitro, and in vivo analyses using zebrafish models

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Fig. 5

AP2M1 is associated with Wnt signaling pathway. A Relative mRNA expression of AXIN2 (Wnt), HES1 (Notch), and GLI1 (Hedgehog) following AP2M1 knockdown in HepG2 cells. Data were quantified and expressed as the mean ± SEM of 3 independent experiments. **p < 0.01, ***p < 0.001 vs. value in the negative control. B Relative mRNA expression of AXIN2 (Wnt), HES1 (Notch), and GLI1 (Hedgehog) following AP2M1 knockdown in Hep3B cells. Data were quantified and expressed as the mean ± SEM of 3 independent experiments. **p < 0.01, ***p < 0.001 vs. value in the negative control. C Relative mRNA expression of axin2 (Wnt), her6 (Notch), and gli1 (Hedgehog) in 48hpf zebrafish embryos was detected by RT-PCR. Data were quantified and expressed as the mean ± SEM of 3 independent experiments. **p < 0.01 and ***p < 0.001 vs. value in the negative control

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This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Eur J Med Res