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Fig. 8

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ZDB-FIG-250813-36

Publication

Zimmerman et al., 2025 - Investigating Psychopharmaceutical Effects on Early Vertebrate Development Using a Zebrafish Model System

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Fig. 8

(A–D) Neuronal density in developing brain regions of zebrafish following AY9944 and psychopharmaceutical exposure. HuC/D immunohistochemistry is used to measure fluorescent intensity and evaluate neuronal density in the optic tectum (A), cerebellum (B), midbrain (C), and forebrain (D) in VEH and AY9944 exposed zebrafish compared to CAR, ARI, and TRZ exposed zebrafish. N ≥ 4 and 4 areas per brain region were measured/zebrafish. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, determined by one-way ANOVA followed by Tukey’s post hoc HSD. VEH = 0.1% DMSO, AY9944 = positive control, CAR = Cariprazine, ARI = Aripiprazole, TRZ = Trazodone. Error Bars = 95% confidence intervals.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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