Fig. 7
(A–F) Effect of AY9944 and psychopharmaceutical exposure on the development of brain regions in developing zebrafish. (A) Forebrain area, (B) forebrain length, (C) area of the optic tectum, (D) distance between optic tectums, (E) midbrain area, (F) cerebellar area in VEH and AY9944-treated zebrafish compared to CAR, ARI, and TRZ-treated zebrafish. N ≥ 8 zebrafish. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, determined by one-way ANOVA followed by Tukey’s post hoc HSD. VEH = 0.1% DMSO, AY9944 = positive control, CAR = Cariprazine, ARI = Aripiprazole, TRZ = Trazodone. Error Bars = 95% confidence intervals. |