Fig. 3
(A–E) Morphological measurements of zebrafish following exposure to AY9944 and psychopharmaceuticals. (A) Measurements i-iii were taken from the lateral view. Measurement i: eye width, measures the anterior portion of the eye to the most posterior side of the eye. Measurement ii: rump length, measures the anterior portion of the eye to the anus. Measurement iii: standard length, measures the anterior portion of the eye to the most posterior portion of the tail. Measurement iv: Distance between eyes measures the distance along the most lateral position of one to the other eye (dorsal view). Scale bar: 100 µm. (B) Eye width (C) Distance between the eyes (D) Rump length (E) Standard length. N ≥ 4 with at least 30 fish per trial. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, determined by one-way ANOVA followed by Tukey’s post hoc HSD. VEH = 0.1% DMSO, AY9944 = positive control, CAR = Cariprazine, ARI = Aripiprazole, TRZ = Trazodone. Error Bars = 95% confidence intervals. |