FIGURE
Fig. 3 - Supplemental 2
- ID
- ZDB-FIG-250808-49
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- Wu et al., 2025 - Pu.1/Spi1 dosage controls the turnover and maintenance of microglia in zebrafish and mammals
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Fig. 3 - Supplemental 2
Microglia number is not affected in pu.1Δ839 null mutants. (A) Representative images show the co-staining of eGFP and Lcp1 antibodies on the midbrain cross section of adult pu.1Δ839/+;TgBAC(ccl34b.1:eGFP) and pu.1Δ839/Δ839;TgBAC(ccl34b.1:eGFP) fish. eGFP+ cells represent microglia, whereas eGFP-Lcp1+ cells are dendritic cells (DCs). (B) Quantification of the number of eGFP+ microglia and eGFP-Lcp1+ DCs on the midbrain cross section of adult pu.1Δ839/+;TgBAC(ccl34b.1:eGFP) (n=6) and pu.1Δ839/Δ839;TgBAC(ccl34b.1:eGFP) (n=5) fish. n.s.=not significant, p>0.05. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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