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Fig. 2

ID

ZDB-FIG-250526-61

Publication

Shi et al., 2025 - Gastrodin promotes CNS myelinogenesis and alleviates demyelinating injury by activating the PI3K/AKT/mTOR signaling

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Fig. 2

Gastrodin promotes myelin sheath formation.

a Schematic of Tg(MBP:Gal4) & Tg(5×UAS:GFP) imaging pipeline. b Representative images showing lateral views of the spinal cords at 5 dpf. c Quantification of GFP⁺ cells number in the ventral or dorsal spinal cord (n = 12–14 zebrafish). d Schematic of DNA microinjection and imaging pipeline. e Time-lapse imaging of myelin sheath development of a single OL from 3 dpf to 7 dpf. f Representative images showing myelin sheaths formed by a single OL at 7 dpf and quantification of myelin sheath number per OL (n = 42–60 OLs). Data are represented as mean ± SEM, unpaired Student’s t test in c and f.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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