Fig. 6

Panx2 ablation affects visual-motor response to light-ON and light-OFF stimuli in larvae. Principal component analysis was performed using multivariable activity data. a) The variable correlation plot indicates the coordinates of seven variables within the first two dimensions, where PC1 and PC2 capture 73.62 % and 15.14 % of the data variance, respectively. b) Line graph showing patterns of immobility with mean freeze duration activity for Panx2+/+ (red) and Panx2Δ11 (blue) over alternating 20-min periods of light-ON and light-OFF conditions. c) Line graph showing the mean average activity. Mean activity, with error bars showing SD for d) light-ON and e) light-OFF conditions, ****P-value<0.0001. f) Line graph showing the mean average activity for Panx2+/+ (red) and Panx2Δ11 (blue) during an initial light-OFF period, followed by 20-min increments of increasing light intensities. Mean activity, with error bars showing SD during g) 10 % light intensity, h) 20 % light intensity and i) 30 % light intensity. ****P-value<0.0001. Data shown for n = 24 larvae for each genotype. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)