Fig. 5

Light-ON and light-OFF conditions affect free swimming of Panx2Δ11 larvae. Representative images of a single-well showing examples of Panx2+/+ and Panx2Δ11 larvae locomotion patterns in the light (a). Medium (<20 mm/s) or high-speed movements (>20 mm/s) are visualized with green and red colors, respectively. Graphs demonstrate mean experimental traces ±95 % CI of distance traveled (mm) and speed (mm/s) of 6 dpf larvae for 30 min (b,c) and their corresponding mean values, in the light. d) Representative images for each genotype, in the dark. Tracked experimental traces of distance and speed under dark conditions (e,f) and their corresponding mean ± SD. Sample sizes were n = 24 larvae for each genotype. A Welch's t-test was used for statistical comparison between groups. Significance: ****P-value<0.0001 and *P-value<0.05. Error bars = SD. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)