FIGURE

Fig. 3

ID

ZDB-FIG-250423-10

Publication

Lin et al., 2025 - Toosendanin-induced liver damage through irreparable DNA damage and autophagy flow blockade

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Fig. 3

MD simulation of TO-mTOR complex. (A) RMSD analyses demonstrated the stability of mTOR protein and its binding structures with TO. (B) The Rg of complex varies with time. (C) RMSF analyses indicate the binding stability of mTOR protein residues with TO. (D) H-bond occupancy of amino acids within the complexes. (E) Number of hydrogen bonds per ns. (F) Energy changes in the TO-mTOR complex over 50 ns during MD simulations.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Phytomedicine : international journal of phytotherapy and phytopharmacology, 140, Lin, Y., Zhang, J., Gao, X., Wu, Z., Yang, L., Tian, K., Lv, X., Li, J., Chen, K., Zhang, Y., Hu, H., Zhu, A., Toosendanin-induced liver damage through irreparable DNA damage and autophagy flow blockade, 156586156586, Copyright (2025) with permission from Elsevier. Full text @ Phytomedicine