FIGURE

Figure 2

ID

ZDB-FIG-250127-189

Publication

Ren et al., 2024 - Knockout of dhx38 Causes Inner Ear Developmental Defects in Zebrafish

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Figure 2

The expressions of some specification-related inner ear markers differed significantly between the sibling and dhx38⁻^/− mutant embryos: (A) The expressions of two otic matrix protein markers were normal at 36 hpf in the sibling and dhx38⁻^/− mutant embryos. Scale bar: 100 µm. (B) Two otic matrix protein markers displayed slight declines at 48 hpf and 56 hpf. Scale bar: 40 µm. (C) The in situ staining of markers for semicircular canal sensory cristae (bmp4), and saccular and utricular maculae marker (cahz), respectively. Scale bar: 40 µm. The epithelial pillar of the semicircular canal (ncs-1a), semicircular canal projections (dacha), and cilia (foxj1b). Scale bar: 100 µm. The red arrows indicate signal spots.

Expression Data

Genes:	bmp4 cahz dacha foxj1b ncs1a otomp stm
Fish:	WT dhx38^hzu20/hzu20
Anatomical Terms:	inner ear macula utricle otolith saccule semicircular canal
Stage Range:	Prim-25 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	dhx38^hzu20/hzu20
Observed In:	inner ear inner ear development macula utricle otolith saccule semicircular canal
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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