Gene

dacha

ID

ZDB-GENE-020402-3

Name

dachshund a

Symbol

dacha Nomenclature History

Previous Names

dachA

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within inner ear development. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including nervous system; neural crest; optic vesicle; otic vesicle; and solid lens vesicle. Orthologous to human DACH2 (dachshund family transcription factor 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from 8 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dacha Human Ortholog

No data available

Associated With dacha Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003380	SKI/SNO/DAC domain
Family	IPR052417	Dachshund domain-containing protein
Homologous_superfamily	IPR009061	Putative DNA-binding domain superfamily
Homologous_superfamily	IPR037000	Ski-like, DNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Dachshund domain-containing protein	Putative DNA-binding domain superfamily	Ski-like, DNA-binding domain superfamily	SKI/SNO/DAC domain
UniProtKB:F1R0U6 InterPro	602
UniProtKB:A0A8M3AX28 InterPro	604
UniProtKB:A0A8M2B8M1 InterPro	601
UniProtKB:A0A8M3AME8 InterPro	605
UniProtKB:A0A8M9PCG2 InterPro	583