Gene
foxj1b
- ID
- ZDB-GENE-041212-76
- Name
- forkhead box J1b
- Symbol
- foxj1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within cilium assembly and embryonic organ morphogenesis. Predicted to be located in nucleus. Is expressed in several structures, including axis; germ ring; mesoderm; nervous system; and pronephros. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 43. Orthologous to human FOXJ1 (forkhead box J1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 20 figures from 17 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ciliary dyskinesia 43 | Alliance | Ciliary dyskinesia, primary, 43 | 618699 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018122 | Fork head domain conserved site1 |
| Conserved_site | IPR030456 | Fork head domain conserved site 2 |
| Domain | IPR001766 | Fork head domain |
| Domain | IPR047512 | Forkhead box protein J1, forkhead domain |
| Family | IPR047513 | Forkhead box protein J1 |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Forkhead box protein J1 | Forkhead box protein J1, forkhead domain | Fork head domain | Fork head domain conserved site1 | Fork head domain conserved site 2 | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1R8Z9
|
442 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
foxj1b-201
(1)
|
Ensembl | 2,316 nt | ||
| mRNA |
foxj1b-202
(1)
|
Ensembl | 828 nt | ||
| mRNA |
foxj1b-203
(1)
|
Ensembl | 1,343 nt |
Interactions and Pathways
No data available
Plasmids
No data available