FIGURE

Figure 11

ID

ZDB-FIG-241019-60

Publication

Wijerathna et al., 2024 - CRISPR/Cas9-Mediated fech Knockout Zebrafish: Unraveling the Pathogenesis of Erythropoietic Protoporphyria and Facilitating Drug Screening

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Figure 11

Changes in temporal macrophage production in fech^−/− larvae. (A) Alterations in macrophage production in the heads, trunks, and tails of WT and fech^−/− zebrafish larvae during different developmental stages. (B) The total number of macrophages counted in WT and fech^−/− larvae at various developmental stages. The highest macrophage counts for fech^−/− larvae, compared with those for the WT, were observed at 4 dpf. Total macrophage counts are presented as the means ± SD (n = 5). Statistical significance between WT and fech^−/− larvae was analyzed using Student’s t-test (ns, non-significant; ****, p ≤ 0.0001).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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