FIGURE

Figure 6

ID

ZDB-FIG-241019-55

Publication

Wijerathna et al., 2024 - CRISPR/Cas9-Mediated fech Knockout Zebrafish: Unraveling the Pathogenesis of Erythropoietic Protoporphyria and Facilitating Drug Screening

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Figure 6

Apoptosis activation in fech^−/− larvae. (A) Acridine orange staining of WT and fech^−/− larvae at various developmental stages and (B) relative fluorescence intensity. (C) The bax/bcl2 mRNA fold induction ratios in WT and fech^−/− larvae at different developmental stages. The fold induction ratios are presented as the means ± SD (n = 3). Statistical significance between fech^−/− and WT larvae was analyzed using Student’s t-test (ns, non-significant; *, p ≤ 0.1; **, p ≤ 0.01; ****, p ≤ 0.0001).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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