FIGURE

Figure 7

ID

ZDB-FIG-241019-56

Publication

Wijerathna et al., 2024 - CRISPR/Cas9-Mediated fech Knockout Zebrafish: Unraveling the Pathogenesis of Erythropoietic Protoporphyria and Facilitating Drug Screening

Other Figures

All Figure Page

Back to All Figure Page

Figure 7

Effect of UDCA treatment on apoptosis in fech^−/− larvae. (A) Acridine orange staining of WT and fech^−/− larvae after UDCA treatment and (B) relative fluorescence intensity. (C) The bax/bcl2 expression ratio after UDCA treatment. The bax/bcl2 fold induction ratios are presented as the means ± SD (n = 3). Statistical significance between fech^−/− and WT larvae was analyzed using Student’s t-test (ns, non-significant; *, p ≤ 0.1; ***, p ≤ 0.001; ****, p ≤ 0.0001).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.