FIGURE

Fig. 1

ID

ZDB-FIG-240829-62

Publication

Camussi et al., 2024 - Delving into the Complexity of Valproate-Induced Autism Spectrum Disorder: The Use of Zebrafish Models

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

Effect of valproic acid (VPA) on zebrafish larval survival and hatching rates at up to 120 h post-fertilisation (hpf) (n = 120 per group). (A) Kaplan–Meier survival comparison in WT-AB fish showed a significant effect [log-rank (Mantel–Cox) test] of VPA treatment at 100 (p ≤ 0.05), 250, and 500 μM (p ≤ 0.0001) as compared with untreated controls (CTRL) as early as 24 hpf. (B) The hatching rate of WT-AB fish was significantly affected [log-rank (Mantel–Cox) test] by VPA treatment with doses of 100 (p ≤ 0.05), 250, and 500 μM (p ≤ 0.0001) at 72 hpf. (C,D) Survival and hatching rates of Tg(mpeg1:EGFP) transgenic fish were not influenced by any tested treatment (p > 0.05).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cells