Fig. 4
Effects of valproic acid (VPA) on locomotor behaviour in WT-AB larvae at 120 h post-fertilisation (hpf) (n = 24 per group). (A) Startle response data analysis showed significant dose-dependent reductions of larval locomotor activity, both before and after the mechanical stimulation (** p ≤ 0.01, *** p ≤ 0.001, **** p ≤ 0.0001, two-way ANOVA test). (B) Visual motor response data analysis showed significant dose-dependent reductions of larval locomotor performance in both dark and light conditions (* p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001, **** p ≤ 0.0001, two-way ANOVA test). Data are represented as means ± SEM |