FIGURE

Fig. 7

ID

ZDB-FIG-240816-30

Publication

Gait�n-Pe�as et al., 2024 - Characterization of ClC-1 chloride channels in zebrafish: a new model to study myotonia

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Fig. 7

RESCUE OF MOVEMENT DEFECTS BY MYTONIA MUTATIONS AND OTHER CLC CHANNELS A, total distance parameter recorded during the SEM test for each group. B, histogram showing the frequency of the distances travelled by each group during the SEM test. C, total distance parameter recorded during the MIM test for each group. In A and C, bars represent means � SD of the total distance, where each dot represents a single larva (A; cr_control, n = 133; cr_clcn1a+b, n = 73; cr_clcn1a+b + hClC-1, n = 22; cr_clcn1a+b + hClC-1 M485V, n = 56; cr_clcn1a+b + hClC-1 P480L, n = 34; cr_clcn1a+b + hClC-1 I290M, n = 43; cr_clcn1a+b + rClC-2, n = 29. C; cr_control, n = 36; cr_clcn1a+b, n = 31; cr_clcn1a+b + hClC-1, n = 17; cr_clcn1a+b + hClC-1 M485V, n = 28; cr_clcn1a+b + hClC-1 P480L, n = 29; cr_clcn1a+b + hClC-1 I290M, n = 29; cr_clcn1a+b + rClC-2, n = 31). The graphs show the accumulation of 2?3 independent experiments (N = 2?3). Statistical analysis according to ordinary one-way ANOVA followed by uncorrected Fisher's LSD (A) or Kruskal?Wallis followed by uncorrected Dunn's multiple comparisons test

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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