FIGURE

Fig. 1

ID

ZDB-FIG-240816-24

Publication

Gaitán-Peñas et al., 2024 - Characterization of ClC-1 chloride channels in zebrafish: a new model to study myotonia

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Fig. 1

GENOMIC ANALYSIS OF THE CLCN1 GENES A, genomic organization of the CLCN1 locus in humans (Hs), mice (Mm), zebrafish (Dr), nile tilapia (On) and mexican tetra (Amx). Several genes around the CLCN1 locus are conserved. B, alignment of the predicted protein sequences of human, mouse, and zebrafish ClC-1 channels performed with CLUSTALW. α-helices are labelled with a black line. The CBS (cystathionine β-synthase) intracellular domains are marked with a blue line. Residues involved in chloride selectivity are highlighted with green background. Exons are typed in alternate black and red. Asterisk indicates identical residues among the five proteins, colon indicates conserved residues, and full stop indicates similar residues.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Physiol.