FIGURE

Fig. 4

ID

ZDB-FIG-240702-85

Publication

Li et al., 2023 - Establishment of a non-alcoholic fatty liver disease model by high fat diet in adult zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

RNA-seq analysis of changes in gene transcript levels during NALFD progression. (A) GSEA analysis of differentially expressed genes with significant upregulation of response pathways to endoplasmic reticulum stress. (B) Bubble plot of GO analysis restlt, lipid synthesis, insulin response and endoplasmic reticulum stress pathways were significantly upregulated. (C) Screening results of cytoHubba app module with the top 20 highest scoring genes. (D) qRT-PCR validation of mRNA expression levels of endoplasmic reticulum stress molecules, fatty acid synthase and insulin substrate receptor (more than three samples were tested for each gene). n.s., no statistical significance, *p < 0.05, **p < 0.01, ***p < 0.001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Animal Model Exp Med