FIGURE

Figure 1

ID

ZDB-FIG-240429-90

Publication

Jiang et al., 2024 - A Mechanistic Study of the Osteogenic Effect of Arecoline in an Osteoporosis Model: Inhibition of Iron Overload-Induced Osteogenesis by Promoting Heme Oxygenase-1 Expression

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Figure 1

ACL exposure caused developmental malformations in zebrafish at high concentrations. (A) The chemical structure of ACL. (B) Locomotion tracks, (C) average speed and (D) total movement distance of zebrafish larvae exposed to 0.01–10 mg/L ACL treatment at 5 dpf (n = 25). (E) Zebrafish embryos survival proportions treated with 0.01–10 mg/L ACL for 10 days. (F) Malformation phenotypes of embryos exposed to 0.01–10 mg/L ACL for 3–5 days. (G) Malformation rate of different concentrations of ACL-treated embryos in 5 dpf (n = 50). (H) Cell viability of MC3T3-E1 cells under various concentrations of ACL for 24 h or 48 h, blank was treated as the control group. Data are expressed as the mean ± standard deviation (SD), * p < 0.05 versus the control group.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Antioxidants (Basel)