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Fig. 4

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ZDB-FIG-240313-12

Publication

Jiao et al., 2023 - Single-cell sequencing reveals the evolution of immune molecules across multiple vertebrate species

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Fig. 4

The characteristics of T cells in evolution. (A) Subsets of T cells in t-SNE space, expression of marker genes and the cell types assigned to each subset were shown from left to right. (B, C) Key genes in TCR signaling pathway conservatively (B) or specifically (C) expressed in different species. The color gradient denotes the level of gene expression, red being high whereas gray being low. (D) Differential usage of TCR signaling cascades were summarized in each species. Components expressed in the species were shown in color while no/low expressed ones were in gray. (E, F) The expression of T cell migration-related genes (E) and T cell homeostasis-related genes (F). The dot color indicates the relative gene expression and the dot size is scaled by the percentage of T cells expressing the gene. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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