FIGURE

Figure 4

ID
ZDB-FIG-231002-367
Publication
Sarkar et al., 2023 - Oxidative and Endoplasmic Reticulum Stress Represent Novel Therapeutic Targets for Choroideremia
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Figure 4

Analysis of ER stress in taurine-treated chmru848 fish and CHMY42X cells. Fish were treated with 100 mM of taurine at 3 dpf and collected at 5 dpf for (A) retinal histology and RT-qPCR analysis of (B) the ER stress markers atf6, bip and atf4 and (C) the oxidative stress markers txn, cat and sod3a. (D) Cells were treated with 100 mM of taurine and the expression of SOD2 and ER stress markers CHOP and BIP was analysed using RT-qPCR. Data are expressed as mean ± SEM from n = 3. * p ≤ 0.05, *** < p ≤ 0.001. Scale bar (50 μm), shown in wt corresponds to all images in panel.

Expression Data
Genes:
Fish:
Condition:
Anatomical Term:
Stage: Day 5

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Condition:
Observed In:
Stage: Day 5

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Antioxidants (Basel)